Background The combined analysis of imaging and functional modalities is supposed to
improve diagnostics of neurodegenerative diseases with advanced data science …

Background. Psychophysiological and cognitive tests as well as other functional studies can
detect pre-symptomatic stages of dementia. When assembled with structural data, cognitive …

Introduction Relationships between brain atrophy patterns of typical aging and Alzheimer's
disease (AD), white matter disease, cognition, and AD neuropathology were investigated via …

Biomarkers for dementia of Alzheimer's type (DAT) are sought to facilitate accurate
prediction of the disease onset, ideally predating the onset of cognitive deterioration. T1 …

Structural neuroimaging has been applied to the identification of individuals with Alzheimer's
disease (AD) and mild cognitive impairment (MCI). However, these methods are greatly …

Background Cognitive decline has been found to be associated with gray matter atrophy
and disruption of functional neural networks in Alzheimer's disease (AD) in structural and …

Objective Alzheimer's disease (AD) is a chronic, degenerative neurological disorder
characterized by progressive cognitive decline and mental behavioral abnormalities. Mild …

Neuroimaging biomarkers that distinguish between changes due to typical brain ageing and
Alzheimer's disease are valuable for determining how much each contributes to cognitive …

Background Intervention against age-related neurodegenerative diseases may be difficult
once extensive structural and functional deteriorations have already occurred in the brain …

Introduction: This study aimed to survey the discrimination power of parameters from
cerebrospinal fluid (CSF) biomarkers, fluorodeoxyglucose uptake on PET (FDG-PET) …