Sterol regulatory element binding protein 1 couples mechanical cues and lipid metabolism
R Bertolio, F Napoletano, M Mano… - Nature …, 2019 - nature.com
Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that
regulate lipid biosynthesis and adipogenesis by controlling the expression of several …
regulate lipid biosynthesis and adipogenesis by controlling the expression of several …
[HTML][HTML] A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans
Sterol regulatory element-binding proteins (SREBPs) activate genes involved in the
synthesis and trafficking of cholesterol and other lipids and are critical for maintaining lipid …
synthesis and trafficking of cholesterol and other lipids and are critical for maintaining lipid …
Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes
H Shimano - Progress in lipid research, 2001 - Elsevier
Roles of sterol regulatory element-binding proteins (SREBPs) have been established as
lipid synthetic transcription factors especially for cholesterol and fatty acid synthesis …
lipid synthetic transcription factors especially for cholesterol and fatty acid synthesis …
SREBP-regulated lipid metabolism: convergent physiology—divergent pathophysiology
H Shimano, R Sato - Nature Reviews Endocrinology, 2017 - nature.com
Cellular lipid metabolism and homeostasis are controlled by sterol regulatory-element
binding proteins (SREBPs). In addition to performing canonical functions in the …
binding proteins (SREBPs). In addition to performing canonical functions in the …
Sterol regulatory element-binding protein family as global regulators of lipid synthetic genes in energy metabolism
H Shimano - 2002 - Elsevier
Sterol regulatory element-binding proteins (SREBPs) have been established as lipid
synthetic transcription factors for cholesterol and fatty acid synthesis. SREBPs are …
synthetic transcription factors for cholesterol and fatty acid synthesis. SREBPs are …
SREBPs: the crossroads of physiological and pathological lipid homeostasis
R Raghow, C Yellaturu, X Deng, EA Park… - Trends in endocrinology …, 2008 - cell.com
The uptake, biosynthesis and metabolism of cholesterol and other lipids are exquisitely
regulated by feedback and feed-forward pathways in organisms ranging from …
regulated by feedback and feed-forward pathways in organisms ranging from …
Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's been
TF Osborne, PJ Espenshade - Genes & development, 2009 - genesdev.cshlp.org
Sterol regulatory element-binding proteins (SREBPs) are a subfamily of basic helix–loop–
helix leucine zipper (bHLH-LZ) transcription factors that are conserved from fungi to humans …
helix leucine zipper (bHLH-LZ) transcription factors that are conserved from fungi to humans …
Genome-wide analysis of SREBP-1 binding in mouse liver chromatin reveals a preference for promoter proximal binding to a new motif
YK Seo, HK Chong, AM Infante, SS Im… - Proceedings of the …, 2009 - National Acad Sciences
Lipid homeostasis in vertebrates is regulated by 3 sterol regulatory element binding protein
(SREBP) isoforms. Here, we identify targets of SREBP-1 in mammalian liver using chromatin …
(SREBP) isoforms. Here, we identify targets of SREBP-1 in mammalian liver using chromatin …
Srebp2: A master regulator of sterol and fatty acid synthesis1
BB Madison - Journal of lipid research, 2016 - ASBMB
334 Journal of Lipid Research Volume 57, 2016 transcript levels of Srebp1a and Srebp1c
(from the Srebpf1 locus) were dramatically reduced, which may be responsible for depletion …
(from the Srebpf1 locus) were dramatically reduced, which may be responsible for depletion …
A new role for sterol regulatory element binding protein 1 transcription factors in the regulation of muscle mass and muscle cell differentiation
V Lecomte, E Meugnier, V Euthine… - … and cellular biology, 2010 - Taylor & Francis
The role of the transcription factors sterol regulatory element binding protein 1a (SREBP-1a)
and SREBP-1c in the regulation of cholesterol and fatty acid metabolism has been well …
and SREBP-1c in the regulation of cholesterol and fatty acid metabolism has been well …