Genotoxic effects and molecular docking of 1, 4-dioxane: Combined protective effects of trans-resveratrol

D Kurt, A Acar, D Çavuşoğlu, E Yalçin… - … Science and Pollution …, 2021 - Springer
In this study, the protective effects of trans-resveratrol (t-resv) against 1, 4-dioxane-induced
toxicity in meristematic cells were investigated. For this purpose, Allium test was used and …

A versatile model for investigating the protective effects of Ceratonia siliqua pod extract against 1,4-dioxane toxicity

K Çavuşoğlu, D Kurt, E Yalçın - Environmental Science and Pollution …, 2020 - Springer
In this study, the toxic effects of 1, 4-dioxane, a common contaminant, and the protective
property of Ceratonia siliqua L. pod extract (Cspe) against this toxicity are aimed to be …

In vivo effects of 1,4-dioxane on genotoxic parameters and behavioral alterations in Drosophila melanogaster

F Turna Demir - Journal of Toxicology and Environmental Health …, 2022 - Taylor & Francis
Dioxane (DXN) is used as solvent in different consumer products including cosmetics,
paints, surfactants, and waxes. In addition, DXN is released as an unwanted contaminating …

Potential genotoxic and biological effects of 1, 4 dioxane on different model organisms

FT Demir, E Demir - Current Opinion in Environmental Science & Health, 2023 - Elsevier
A suspected human carcinogen, the compound 1, 4-dioxane (DXN) has been commonly
employed as a solvent in the production of various cleaning applications, cosmetics, dyes …

Cyto-and geno-toxicity of 1, 4-dioxane and its transformation products during ultraviolet-driven advanced oxidation processes

W Li, E Xu, D Schlenk, H Liu - Environmental Science: Water Research …, 2018 - pubs.rsc.org
Ultraviolet-driven advanced oxidation processes (UV/AOPs) are integral steps in water
reuse treatment trains. The toxicity of trace organic transformation products during a UV/AOP …

In vivo positive mutagenicity of 1, 4-dioxane and quantitative analysis of its mutagenicity and carcinogenicity in rats

M Gi, M Fujioka, A Kakehashi, T Okuno… - Archives of …, 2018 - Springer
Dioxane is a widely used synthetic industrial chemical and its contamination of drinking
water and food is a potential health concern. It induces liver tumors when administered in …

Hybrid of resveratrol and glucosamine: an approach to enhance antioxidant effect against DNA oxidation

LL Bao, ZQ Liu - Chemical Research in Toxicology, 2018 - ACS Publications
Resveratrol exhibits various pharmacological activities, which are dependent upon phenolic
hydroxyl groups. In this work, glucosamine, lipoic acid, or adamantanamine moiety was …

Identification of dose-dependent DNA damage and repair responses from subchronic exposure to 1, 4-dioxane in mice using a systems analysis approach

G Charkoftaki, JP Golla, A Santos-Neto… - Toxicological …, 2021 - academic.oup.com
Dioxane (1, 4-DX) is an environmental contaminant found in drinking water throughout the
United States. Although it is a suspected liver carcinogen, there is no federal or state …

Resveratrol, a natural phenolic compound, inhibits cell proliferation and prevents oxidative DNA damage

A Sgambato, R Ardito, B Faraglia, A Boninsegna… - … /Genetic Toxicology and …, 2001 - Elsevier
Resveratrol (3, 4′, 5-trihydroxystilbene) is a naturally occurring phenolic compound which
is present at high levels in wine and has been recently proposed as a potential cancer …

Lycopene: an antioxidant product reducing dithane toxicity in Alliumcepa L.

O Macar, T Kalefetoğlu Macar, K Çavuşoğlu… - Scientific Reports, 2023 - nature.com
The current study was undertaken to assess the attenuating potential of lycopene against
Dithane toxicity in Allium cepa L. roots. A. cepa bulbs were arranged in 6 groups. The control …