Tuberculosis (TB), caused by the bacterium Mycobacterium tuberculosis, and malaria,
caused by parasites from the Plasmodium genus, are two of the major causes of death due …

Introduction Malaria and tuberculosis are highly infectious diseases declared a global health
emergency by the World Health Organization, and together they account for more than 1.5 …

The emergence and spread of drug-resistant strains of Mycobacterium tuberculosis is
worsening the global threat of tuberculosis (TB). There is a need and urgency for the …

Tuberculosis (TB), caused by Mycobacterium tuberculosis (Mtb), remains a leading cause of
morbidity and mortality in humans worldwide. Currently, the standard treatment for TB …

Despite significant efforts to improve the treatment of tuberculosis (TB), it remains a
prevalent infectious disease worldwide owing to the limitations of current TB therapeutic …

Tuberculosis (TB) drug-development strategies, a wide range of candidate host-directed
therapies (HDT) s-including new and repurposed drugs, biologics, and cellular therapies …

Mycobacterium tuberculosis (Mtb) has coevolved with a human host to evade and exploit the
immune system in multiple ways. Mtb is an enormously successful human pathogen that can …

Highlights•HDT offers novel opportunities as treatment for TB.•HDT may prove useful to
combat MDR and XDR-TB.•Intracellular high-throughput phenotypic assays accelerates …

Tuberculosis (TB) maintains its infamous status regarding its detrimental effect on global
health, causing the highest mortality by a single infectious agent. The presence of resistance …

Tuberculosis (TB) continues to remain at the forefront of the infectious disease burden
globally, albeit with some aberrations during the COVID-19 pandemic. Among many factors …