Nanocatalytic tumor therapy by biomimetic dual inorganic nanozyme‐catalyzed cascade reaction

S Gao, H Lin, H Zhang, H Yao, Y Chen… - Advanced …, 2019 - Wiley Online Library
Emerging nanocatalytic tumor therapies based on nontoxic but catalytically active inorganic
nanoparticles (NPs) for intratumoral production of high‐toxic reactive oxygen species have …

Targeted self-activating Au-Fe3O4 composite nanocatalyst for enhanced precise hepatocellular carcinoma therapy via dual nanozyme-catalyzed cascade reactions

X Wang, T Xiong, M Cui, X Guan, J Yuan, Z Wang… - Applied Materials …, 2020 - Elsevier
Catalytic nanozyme-based tumor therapy is currently considered as a promising strategy in
anti-tumor treatment, but it also has some disadvantages such as systemic toxicity, off-target …

[HTML][HTML] Tumor-selective catalytic nanomedicine by nanocatalyst delivery

M Huo, L Wang, Y Chen, J Shi - Nature communications, 2017 - nature.com
Tumor cells metabolize in distinct pathways compared with most normal tissue cells. The
resulting tumor microenvironment would provide characteristic physiochemical conditions …

Biocatalytic cascade in tumor microenvironment with a Fe2O3/Au hybrid nanozyme for synergistic treatment of triple negative breast cancer

X Zeng, Y Ruan, Q Chen, S Yan, W Huang - Chemical Engineering Journal, 2023 - Elsevier
Designing nanozyme hybrids with cascade catalytic activities and coupling effects has
significant promises in tumor therapy through concerted effects. In this work, a goethite …

GSH‐depleted nanozymes with hyperthermia‐enhanced dual enzyme‐mimic activities for tumor nanocatalytic therapy

S Dong, Y Dong, T Jia, S Liu, J Liu, D Yang… - Advanced …, 2020 - Wiley Online Library
Nanocatalytic therapy, using artificial nanoscale enzyme mimics (nanozymes), is an
emerging technology for therapeutic treatment of various malignant tumors. However, the …

Advanced cobalt-ferrite layered double hydroxides sandwich-structured nanozymes for ROS-bloomed tumor therapy

S Li, X Zhao, H Ding, J Chang, X Qin, F He… - Chemical Engineering …, 2023 - Elsevier
Artificial-engineered nanozymes show great promise for improving cancer therapeutic
outcomes. Herein, we elaborately designed the advanced cobalt-ferrite layered double …

A metal-free nanozyme-activated prodrug strategy for targeted tumor catalytic therapy

Q Liang, J Xi, XJ Gao, R Zhang, Y Yang, X Gao, X Yan… - Nano Today, 2020 - Elsevier
Enzyme-mediated activation of prodrug in tumor cells is an attractive strategy for targeted
cancer therapy. Of note, natural peroxidase and indole-3-acetic acid (IAA) have been shown …

Highly dispersed nano-enzyme triggered intracellular catalytic reaction toward cancer specific therapy

X Mei, T Hu, H Wang, R Liang, W Bu, M Wei - Biomaterials, 2020 - Elsevier
Currently, reactive oxygen species (ROS)-induced apoptosis systems have drawn
increasing attention in cancer therapy, owing to their specific tumor inhibition ability and …

Tumor microenvironment self-regulation: Bimetallic metal nanozyme-derived multifunctional nanodrug for optimizable cascade catalytic reaction-synergetic anti-tumor …

X Jing, L Meng, S Fan, T Yang, N Zhang, R Xu… - Chemical Engineering …, 2022 - Elsevier
The tumor microenvironment (TME) responsive multimodal theranostic nanoplatforms have
attracted great attentions for precision medicine. To design well-defined cascade catalytic …

Tumor‐microenvironment‐responsive cascade reactions by a cobalt‐single‐atom nanozyme for synergistic nanocatalytic chemotherapy

S Cai, J Liu, J Ding, Z Fu, H Li, Y Xiong… - Angewandte …, 2022 - Wiley Online Library
Nanocatalytic therapy, involving the nanozyme‐triggered production of reactive oxygen
species (ROS) in the tumor microenvironment (TME), has demonstrated potential in tumor …