Animal models have played a significant role in research that aims to understand peptic
ulceration. Firstly, they have helped define basic mechanisms of gastric mucosal defence …

Background: Helicobacter pylori infection in humans is a major risk factor for peptic ulcer, but
studies on the relation between H. pylori infection and gastric pathology are limited due to a …

In summary, it appears that the role of H. pylori in duodenal ulcerogenesis is not directly
associated with acid hypersecretion. Similarly, it seems unlikely that H. pylori-induced …

Helicobacter pylori has been implicated in the genesis of human gastritis, dyspepsia, and
peptic ulcers. However, its influence in the quality of experimental gastric ulcer healing has …

Isolation of a spiral-shaped bacterium closely related to Helicobacter pylori from the cat
stomach made it possible to investigate new small animal models of gastric infection. Pure …

The acceptance of Helicobacter pylori as a major human pathogen has necessitated the
development of animal models to help elucidate the pathogenic mechanisms of this …

In order to develop an experimental rodent model, we administered 2 ml (10< sup> 8
organisms/ml) broth culture of any of four human isolated strains of Helicobacter pylori by …

Animal models of microbial diseases in humans are an essential component for determining
fulfillment of Koch's postulates and determining how the organism causes disease, host …

Following the demonstration of Helicobacter pylori as a major gastroduodenal pathogen
there was a need to develop animal models in order to investigate mechanisms of …

Laboratory mice have become one of the best animal species for mechanistic studies in
gastrointestinal research. Their abundant genetic information, the way of causing …