The MCP/eotaxin subfamily of CC chemokines

E Van Coillie, J Van Damme, G Opdenakker - Cytokine & growth factor …, 1999 - Elsevier
Migration of leukocytes from the bone marrow to the circulation, the primary lymphoid organs
and inflammatory sites is directed by chemokines and specific receptor interactions. Besides …

[HTML][HTML] Molecular cloning of a novel human CC chemokine (Eotaxin-3) that is a functional ligand of CC chemokine receptor 3

M Kitaura, N Suzuki, T Imai, S Takagi, R Suzuki… - Journal of Biological …, 1999 - ASBMB
Previously, we mapped the novel CC chemokine myeloid progenitor inhibitory factor 2 (MPIF-
2)/eotaxin-2 to chromosome 7q11. 23 (Nomiyama, H., Osborne, LR, Imai, T., Kusuda, J …

Eotaxin-2, a novel CC chemokine that is selective for the chemokine receptor CCR3, and acts like eotaxin on human eosinophil and basophil leukocytes

U Forssmann, M Uguccioni, P Loetscher… - The Journal of …, 1997 - rupress.org
A novel human CC chemokine consisting of 78 amino acids and having a molecular mass of
8,778.3 daltons (VVIPSPCCMF FVSKRIPENR VVSYQLSSRS TCLKAGVIFT TKKGQQ SCGD …

[HTML][HTML] Eotaxin-3/CCL26 is a natural antagonist for CC chemokine receptors 1 and 5: a human chemokine with a regulatory role

V Petkovic, C Moghini, S Paoletti, M Uguccioni… - Journal of Biological …, 2004 - ASBMB
Eotaxin-3 (CCL26), like eotaxin (CCL11) and eotaxin-2 (CCL24), has long been considered
a specific agonist for CC chemokine receptor 3 (CCR3), attracting and activating …

Eotaxin-3 is a natural antagonist for CCR2 and exerts a repulsive effect on human monocytes

P Ogilvie, S Paoletti, I Clark-Lewis, M Uguccioni - Blood, 2003 - ashpublications.org
Abstract Eotaxin-3 (CCL26) belongs to the group of CC chemokines that attract eosinophils,
basophils, and Th2 lymphocytes. Like eotaxin (CCL11) and eotaxin-2 (CCL24), eotaxin-3 …

[HTML][HTML] Characterization of binding between the chemokine eotaxin and peptides derived from the chemokine receptor CCR3

J Ye, LL Kohli, MJ Stone - Journal of Biological Chemistry, 2000 - ASBMB
The CC chemokine eotaxin plays a predominant role in eosinophil trafficking in vivo by
specifically activating the chemokine receptor CCR3. We have screened a series of …

Cloning and functional characterization of a novel human CC chemokine that binds to the CCR3 receptor and activates human eosinophils

JR White, C Imburgia, E Dul… - Journal of leukocyte …, 1997 - academic.oup.com
Eotaxin has been found to bind exclusively to a single chemokine receptor, CCR3. Using
expression sequence tag screening of an activated monocyte library, a second chemokine …

[HTML][HTML] The ligands of CXC chemokine receptor 3, I-TAC, Mig, and IP10, are natural antagonists for CCR3

P Loetscher, A Pellegrino, JH Gong, I Mattioli… - Journal of Biological …, 2001 - ASBMB
Th1 and Th2 lymphocytes express a different repertoire of chemokine receptors (CCRs).
CXCR3, the receptor for I-TAC (interferon-inducible T cell α-chemoattractant), Mig …

[HTML][HTML] Functional expression of the eotaxin receptor CCR3 in T lymphocytes co-localizing with eosinophils

BO Gerber, MP Zanni, M Uguccioni, M Loetscher… - Current Biology, 1997 - cell.com
Background: The chemokine eotaxin is produced at sites of allergic inflammation, binds
selectively to the chemokine receptor CCR3 and attracts eosinophil and basophil …

Eotaxin is a natural antagonist for CCR2 and an agonist for CCR5

P Ogilvie, G Bardi, I Clark-Lewis… - Blood, The Journal …, 2001 - ashpublications.org
Eotaxin is a potent inducer of eosinophil chemotaxis and was considered as a selective
ligand of the CC chemokine receptor 3 (CCR3), which is expressed on eosinophils …