Spinal cord injury (SCI) is associated with devastating neurological deficits affecting more
than 11,000 Americans each year. Although several therapeutic agents have been …

Spinal cord injury (SCI) patients sustain significant functional impairments; this is causally
related to restricted neuronal regeneration after injury. The ensuing reactive gliosis …

Persons with spinal cord injury (SCI) are in need of effective therapeutics. Estrogen (E2), as
a steroid hormone, is a highly pleiotropic agent; with anti-inflammatory, anti-apoptotic, and …

Spinal cord injury (SCI), depending on the severity of injury, leads to neurological
dysfunction and paralysis. Methylprednisolone, the only currently available therapy renders …

A delayed oligodendrocyte cell death after spinal cord injury (SCI) contributes to chronic
demyelination of spared axons, leading to a permanent neurological deficit. Therefore …

Spinal cord injury (SCI) is a debilitating condition with neurological deficits and loss of motor
function that, depending on the severity, may lead to paralysis. The only treatment currently …

Spinal cord injury (SCI) is a devastating neurologic injury with functional deficits for which
the only currently recommended pharmacotherapy is high‐dose methylprednisolone, which …

Spinal cord injury (SCI) occurs when the spinal cord is damaged from either a traumatic
event or disease. SCI is characterised by multiple injury phases that affect the transmission …

Spinal cord injury (SCI) leads to neurological deficits and motor dysfunction.
Methylprednisolone, the only drug used for treating SCI, renders limited neuroprotection and …

Traumatic brain injury (TBI), which leads to high mortality and morbidity, is a prominent
public health problem worldwide. Neuroinflammation involving microglia and astrocyte …