[HTML][HTML] Machine learning approaches to genome-wide association studies
Abstract Genome-wide Association Studies (GWAS) are conducted to identify single
nucleotide polymorphisms (variants) associated with a phenotype within a specific …
nucleotide polymorphisms (variants) associated with a phenotype within a specific …
[HTML][HTML] Chapter 10: Mining genome-wide genetic markers
Genome-wide association study (GWAS) aims to discover genetic factors underlying
phenotypic traits. The large number of genetic factors poses both computational and …
phenotypic traits. The large number of genetic factors poses both computational and …
[HTML][HTML] Statistical analysis for genome-wide association study
In the past few years, genome-wide association study (GWAS) has made great successes in
identifying genetic susceptibility loci underlying many complex diseases and traits. The …
identifying genetic susceptibility loci underlying many complex diseases and traits. The …
[HTML][HTML] A SUPER powerful method for genome wide association study
Q Wang, F Tian, Y Pan, ES Buckler, Z Zhang - PloS one, 2014 - journals.plos.org
Genome-Wide Association Studies shed light on the identification of genes underlying
human diseases and agriculturally important traits. This potential has been shadowed by …
human diseases and agriculturally important traits. This potential has been shadowed by …
[HTML][HTML] Identifying disease associations via genome-wide association studies
W Huang, P Wang, Z Liu, L Zhang - BMC bioinformatics, 2009 - Springer
Background Genome-wide association studies prove to be a powerful approach to identify
the genetic basis of different human diseases. We studied the relationship between seven …
the genetic basis of different human diseases. We studied the relationship between seven …
A Review for Detecting Gene‐Gene Interactions Using Machine Learning Methods in Genetic Epidemiology
CL Koo, MJ Liew, MS Mohamad… - BioMed research …, 2013 - Wiley Online Library
Recently, the greatest statistical computational challenge in genetic epidemiology is to
identify and characterize the genes that interact with other genes and environment factors …
identify and characterize the genes that interact with other genes and environment factors …
Genetic studies: the linear mixed models in genome-wide association studies
G Li, H Zhu - The Open Bioinformatics Journal, 2013 - openbioinformaticsjournal.com
With the availability of high-density genomic data containing millions of single nucleotide
polymorphisms and tens or hundreds of thousands of individuals, genetic association study …
polymorphisms and tens or hundreds of thousands of individuals, genetic association study …
Bioinformatics challenges for genome-wide association studies
Motivation: The sequencing of the human genome has made it possible to identify an
informative set of> 1 million single nucleotide polymorphisms (SNPs) across the genome …
informative set of> 1 million single nucleotide polymorphisms (SNPs) across the genome …
[HTML][HTML] GWAS to identify SNPs associated with common diseases and individual risk: Genome Wide Association Studies (GWAS) to identify SNPs associated with …
G Hettiarachchi, AA Komar - … : Human Variation and a Coming Revolution …, 2022 - Springer
Association studies have enabled the exploration of alternative, more efficient methods for
early detection, prevention and treatment of diseases by providing valuable insight into their …
early detection, prevention and treatment of diseases by providing valuable insight into their …
An overview of genome-wide association studies
M Chang, L He, L Cai - Computational Systems Biology: Methods and …, 2018 - Springer
Genome-wide association study (GWAS) is a powerful study design to identify genetic
variants of a trait and, in particular, detect the association between common single …
variants of a trait and, in particular, detect the association between common single …