Alpha-glycosyl isoquercitrin alleviates subchronic social defeat stress-induced depression symptoms by modulating the microbiota-gut-brain axis in mice

H Liu, J Li, S Takahashi, A Toyoda, R Inoue… - Life Sciences, 2024 - Elsevier
Aims Increasing evidence suggests a link between gut microbial dysbiosis and the
pathogenesis of depression. Alpha-glycosyl isoquercitrin (AGIQ), consisting of isoquercitrin …

Quercetin reshapes gut microbiota homeostasis and modulates brain metabolic profile to regulate depression-like behaviors induced by CUMS in rats

B Li, Y Yan, T Zhang, H Xu, X Wu, G Yao, X Li… - Frontiers in …, 2024 - frontiersin.org
Quercetin, an abundant flavonoid compound in plants, is considered a novel antidepressant;
however, its mechanisms of action are poorly understood. This study aimed to investigate …

Exploring the potential antidepressant mechanisms of puerarin: Anti-inflammatory response via the gut-brain axis

X Song, W Wang, S Ding, Y Wang, L Ye, X Chen… - Journal of Affective …, 2022 - Elsevier
Background Puerarin has been shown to have a good antidepressant effect, and our
previous study found that it can remedy stress-induced dysbiosis. However, its gut …

[HTML][HTML] Jia Wei Xiao Yao San ameliorates chronic stress-induced depression-like behaviors in mice by regulating the gut microbiome and brain metabolome in …

S Ji, S Han, L Yu, L Du, Y You, J Chen, M Wang, S Wu… - Phytomedicine, 2022 - Elsevier
Background The pathogenesis of depression remains largely unknown. Accumulating
evidence demonstrates the existence of a complex relationship between gut microbiome …

Lactocaseibacillus rhamnosus zz-1 Supplementation Mitigates Depression-Like Symptoms in Chronic Stress-Induced Depressed Mice via the Microbiota–Gut–Brain …

J Xu, M Tang, D Wang, X Zhang, X Yang… - ACS Chemical …, 2023 - ACS Publications
Accumulating evidence has revealed an association between depression and disordered
intestinal microecology. The discovery of psychobiotics has provided a promising …

Puerarin ameliorates depression-like behaviors of with chronic unpredictable mild stress mice by remodeling their gut microbiota

X Song, W Wang, S Ding, X Liu, Y Wang… - Journal of Affective …, 2021 - Elsevier
Background Puerarin is an isoflavone derivative isolated from the traditional Chinese
medicine Pueraria Lobelia, which has proven to relieve depression-like behavior. However …

Eucommiae cortex polysaccharides attenuate gut microbiota dysbiosis and neuroinflammation in mice exposed to chronic unpredictable mild stress: beneficial in …

M Wang, P Sun, Z Li, J Li, X Lv, S Chen, X Zhu… - Journal of Affective …, 2023 - Elsevier
Background Chronic stress alters gut microbiota composition, as well as induces
inflammatory responses and behavioral deficits. Eucommiae cortex polysaccharides (EPs) …

The alteration of gut microbiota in venlafaxine-ameliorated chronic unpredictable mild stress-induced depression in mice

W Shen, Y Tao, F Zheng, H Zhou, H Wu, H Shi… - Behavioural brain …, 2023 - Elsevier
Depression is associated with intestinal dysbiosis. Venlafaxine is a commonly used
antidepressant in clinical practice as a serotonin and noradrenaline reuptake inhibitor …

Dihydroartemisinin Protects Mice from CUMS-induced Depression-like Behaviors by Regulating Gut Microbes

C Tang, H Liu, H Zou, M Su, H Yin, M Sun, Y Zhao… - Neuroscience, 2024 - Elsevier
Depression is one of the most common forms of psychopathology, which is associated with
gut microbiota dysfunction. Dihydroartemisinin (DHA) has been shown to regulate gut …

Gut microbiota mediated inflammation, neuroendocrine and neurotrophic functions involved in the antidepressant-like effects of diosgenin in chronic restraint stress

JJ Cui, ZY Huang, YH Xie, JB Wu, GH Xu, CF Li… - Journal of Affective …, 2023 - Elsevier
Background Diosgenin is a well-known steroid saponin possessing neuroprotective
activities. However, it is unknown whether diosgenin could alleviate depression-like …