Molecular mechanisms of hepatic fibrosis in non-alcoholic steatohepatitis

K Rombouts, F Marra - Digestive diseases, 2010 - karger.com
Non-alcoholic fatty liver disease (NAFLD) has become the most common liver disease in
Western countries. The more severe form of this condition, non-alcoholic steatohepatitis …

Inflammation and fibrogenesis in steatohepatitis

H Fujii, N Kawada - Journal of gastroenterology, 2012 - Springer
Nonalcoholic fatty liver disease consists of a range of disorders characterized by excess
accumulation of triglyceride within the liver. Whereas simple steatosis is clinically benign …

[HTML][HTML] The cellular pathways of liver fibrosis in non-alcoholic steatohepatitis

N Méndez-Sánchez, A Valencia-Rodríguez… - Annals of …, 2020 - ncbi.nlm.nih.gov
Non-alcoholic steatohepatitis (NASH) is considered the advanced stage of non-alcoholic
fatty liver disease (NAFLD). It is characterized by liver steatosis, inflammation and different …

[HTML][HTML] Liver fibrogenesis in non-alcoholic steatohepatitis

Z Bian, X Ma - Frontiers in physiology, 2012 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is emerging as one of the most common chronic
liver diseases in developed western countries. Non-alcoholic steatohepatitis (NASH) is the …

Determinants of fibrosis progression and regression in NASH

D Schuppan, R Surabattula, XY Wang - Journal of hepatology, 2018 - Elsevier
Cirrhosis has become the major liver-related clinical endpoint in non-alcoholic
steatohepatitis (NASH). However, progression to cirrhosis is less predictable in NASH than …

[HTML][HTML] Non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH)-related liver fibrosis: mechanisms, treatment and prevention

F Tacke, R Weiskirchen - Annals of Translational Medicine, 2021 - ncbi.nlm.nih.gov
Liver fibrosis is the excessive expression and accumulation of extracellular matrix proteins in
the liver. Fibrotic scarring occurs as the consequence of chronic injury and inflammation …

Liver fibrosis in the context of nonalcoholic steatohepatitis: the role of adipokines.

M Pastore, F Marra - Minerva gastroenterologica e dietologica, 2017 - europepmc.org
Liver fibrosis is a multifaceted process that occurs as a consequence of chronic liver injury.
This process is characterized by inflammation, activation of matrix-producing cells, matrix …

Liver fibrogenesis and metabolic factors

R Anty, M Lemoine - Clinics and research in hepatology and …, 2011 - Elsevier
Mechanisms of liver fibrosis are complex and varied. Among them, metabolic factors are
particularly important in the development of fibrosis associated with nonalcoholic …

Fibrogenesis in nonalcoholic steatohepatitis

S De Minicis, G Svegliati-Baroni - Expert review of …, 2011 - Taylor & Francis
Nonalcoholic steatohepatitis includes a wide spectrum of liver injury, ranging from simple
inflammation to fibrosis and cirrhosis. Whereas simple steatosis has a benign clinical …

Mechanisms of fibrosis development in nonalcoholic steatohepatitis

RF Schwabe, I Tabas, UB Pajvani - Gastroenterology, 2020 - Elsevier
Nonalcoholic fatty liver disease is the most prevalent liver disease worldwide, affecting 20%–
25% of the adult population. In 25% of patients, nonalcoholic fatty liver disease progresses …