Figure of merit for CRISPR-based nucleic acid-sensing systems: Improvement strategies and performance comparison
Clustered regularly interspaced short palindromic repeats (CRISPR)-based nucleic acid-
sensing systems have grown rapidly in the past few years. Nevertheless, an objective …
sensing systems have grown rapidly in the past few years. Nevertheless, an objective …
Challenges and opportunities for clustered regularly interspaced short palindromic repeats based molecular biosensing
Clustered regularly interspaced short palindromic repeats, CRISPR, has recently emerged
as a powerful molecular biosensing tool for nucleic acids and other biomarkers due to its …
as a powerful molecular biosensing tool for nucleic acids and other biomarkers due to its …
CRISPR/cas systems redefine nucleic acid detection: principles and methods
M Wang, R Zhang, J Li - Biosensors and Bioelectronics, 2020 - Elsevier
Methods that enable rapid, sensitive and specific analyses of nucleic acid sequences have
positive effects on precise disease diagnostics and effective clinical treatments by providing …
positive effects on precise disease diagnostics and effective clinical treatments by providing …
[HTML][HTML] Challenges and perspectives of CRISPR-based technology for diagnostic applications
S Del Giovane, N Bagheri, AC Di Pede… - TrAC Trends in …, 2024 - Elsevier
The precision and versatility of CRISPR-based techniques, combined with the advantages of
nucleic acid-based nanotechnology, hold great promise in transforming the landscape of …
nucleic acid-based nanotechnology, hold great promise in transforming the landscape of …
Advancing sensing technology with CRISPR: From the detection of nucleic acids to a broad range of analytes–a review
S Xie, Z Ji, T Suo, B Li, X Zhang - Analytica Chimica Acta, 2021 - Elsevier
The CRISPR/Cas technology, derived from an adaptive immune system in bacteria, has
been awarded the Nobel Prize in Chemistry in 2020 for its success in gene editing …
been awarded the Nobel Prize in Chemistry in 2020 for its success in gene editing …
Nucleic Acid Enzyme‐Activated CRISPR‐Cas12a With Circular CRISPR RNA for Biosensing
Abstract clustered regularly interspaced short palindromic repeats (CRISPR)‐Cas systems
are increasingly used in biosensor development. However, directly translating recognition …
are increasingly used in biosensor development. However, directly translating recognition …
The CRISPR/Cas system: a customizable toolbox for molecular detection
Y He, W Yan, L Long, L Dong, Y Ma, C Li, Y Xie, N Liu… - Genes, 2023 - mdpi.com
Clustered regularly interspaced short palindromic repeats (CRISPR) and their associated
proteins (Cas) are promising molecular diagnostic tools for rapidly and precisely elucidating …
proteins (Cas) are promising molecular diagnostic tools for rapidly and precisely elucidating …
Evolution of CRISPR-enabled biosensors for amplification-free nucleic acid detection
CRISPR biosensors enable rapid and accurate detection of nucleic acids without resorting
to target amplification. Specifically, these systems facilitate the simultaneous detection of …
to target amplification. Specifically, these systems facilitate the simultaneous detection of …
Powerful CRISPR-based biosensing techniques and their integration with microfluidic platforms
B Chen, Y Li, F Xu, X Yang - Frontiers in bioengineering and …, 2022 - frontiersin.org
In the fight against the worldwide pandemic coronavirus disease 2019 (COVID-19), simple,
rapid, and sensitive tools for nucleic acid detection are in urgent need. PCR has been a …
rapid, and sensitive tools for nucleic acid detection are in urgent need. PCR has been a …
CRISPR‐Cas biochemistry and CRISPR‐based molecular diagnostics
Polymerase chain reaction (PCR)‐based nucleic acid testing has played a critical role in
disease diagnostics, pathogen surveillance, and many more. However, this method requires …
disease diagnostics, pathogen surveillance, and many more. However, this method requires …