Autoinducer-2 Plays a Crucial Role in Gut Colonization and Probiotic Functionality of Bifidobacterium breve UCC2003

SEA Christiaen, M O'Connell Motherway, F Bottacini… - PLoS …, 2014 - journals.plos.org
In the present study we show that lux S of Bifidobacterium breve UCC2003 is involved in the
production of the interspecies signaling molecule autoinducer-2 (AI-2), and that this gene is …

Bifidobacterium breve UCC2003 surface exopolysaccharide production is a beneficial trait mediating commensal-host interaction through immune modulation and …

S Fanning, LJ Hall, D van Sinderen - Gut microbes, 2012 - Taylor & Francis
Bifidobacteria constitute a substantial proportion of the human gut microbiota. There are
currently many bifidobacterial strains with claimed probiotic attributes. The mechanism …

Bifidobacteria exhibit LuxS-dependent autoinducer 2 activity and biofilm formation

Z Sun, X He, VF Brancaccio, J Yuan, CU Riedel - PLoS One, 2014 - journals.plos.org
Autoinducer-2 (AI-2) molecules are one class of signalling molecules involved in gene
regulation dependent on population density in a mechanism commonly referred to as …

Development of a luciferase-based reporter system to monitor Bifidobacterium breve UCC2003 persistence in mice

M Cronin, RD Sleator, C Hill, GF Fitzgerald… - BMC microbiology, 2008 - Springer
Background Probiotics such as bifidobacteria have been shown to maintain a healthy
intestinal microbial balance and help protect against infections. However, despite these …

Bifidobacterium spp. influences the production of autoinducer-2 and biofilm formation by Escherichia coli O157: H7

Y Kim, JW Lee, SG Kang, S Oh, MW Griffiths - Anaerobe, 2012 - Elsevier
The effect of Bifidobacterium spp. on the production of quorum-sensing (QS) signals and
biofilm formation by enterohemorrhagic Escherichia coli (EHEC) O157: H7 was investigated …

Transcription of two adjacent carbohydrate utilization gene clusters in Bifidobacterium breve UCC2003 is controlled by LacI-and repressor open reading frame kinase …

KJ O'Connell, M O'Connell Motherway… - Applied and …, 2014 - Am Soc Microbiol
Members of the genus Bifidobacterium are commonly found in the gastrointestinal tracts of
mammals, including humans, where their growth is presumed to be dependent on various …

The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract

MA Schell, M Karmirantzou, B Snel… - Proceedings of the …, 2002 - National Acad Sciences
Bifidobacteria are Gram-positive prokaryotes that naturally colonize the human
gastrointestinal tract (GIT) and vagina. Although not numerically dominant in the complex …

A two-component regulatory system controls autoregulated serpin expression in Bifidobacterium breve UCC2003

P Alvarez-Martin, M O'Connell Motherway… - Applied and …, 2012 - Am Soc Microbiol
This work reports on the identification and molecular characterization of a two-component
regulatory system (2CRS), encoded by serRK, which is believed to control the expression of …

Bifidobacterial surface-exopolysaccharide facilitates commensal-host interaction through immune modulation and pathogen protection

S Fanning, LJ Hall, M Cronin, A Zomer… - Proceedings of the …, 2012 - National Acad Sciences
Bifidobacteria comprise a significant proportion of the human gut microbiota. Several
bifidobacterial strains are currently used as therapeutic interventions, claiming various …

Analysis of Host-Inducing Proteome Changes in Bifidobacterium longum NCC2705 Grown in Vivo

J Yuan, B Wang, Z Sun, X Bo, X Yuan… - Journal of Proteome …, 2008 - ACS Publications
To investigate the molecular mechanisms underlying the adaptation of Bifidobacterium
longum to the intestinal tract, we utilized a new model for rabbit intestinal culture of B …