Drug repositioning is the process of identifying novel therapeutic potentials for existing drugs
and discovering therapies for untreated diseases. Drug repositioning, therefore, plays an …

Computational drug repositioning or repurposing is a promising and efficient tool for
discovering new uses from existing drugs and holds the great potential for precision …

Efforts to maximize the indications potential and revenue from drugs that are already
marketed are largely motivated by what Sir James Black, a Nobel Prize-winning …

Drug discovery is a time-consuming, high-investment, and high-risk process in traditional
drug development. Drug repositioning has become a popular strategy in recent years …

Drug repositioning is a powerful method that can assists the conventional drug discovery
process by using existing drugs for treatment of a disease rather than its original indication …

Highlights•Understanding the existing drug repositioning methods with a top-down
flowchart.•Prioritizing repositioning methods using their integrated knowledge and …

Drug repositioning aims to find new indications for existing drugs in order to reduce drug
development cost and time. Currently, there are numerous stories of successful drug …

Drug repositioning can drastically decrease the cost and duration taken by traditional drug
research and development while avoiding the occurrence of unforeseen adverse events …

Drug repositioning, the process of discovering, validating, and marketing previously
approved drugs for new indications, is of growing interest to academia and industry due to …

The wealth of knowledge and omic data available in drug research allowed the rising of
several computational methods in drug discovery field yielding a novel and exciting …