I. Introduction U NTIL 35 yr ago, most scientists did not take research on the pineal gland
seriously. The decade beginning in 1956, however, provided several discoveries that laid …

Introduction T HE PINEAL gland has received increasing interest from investigators during
the past decade. As the pineal has become more intensively investigated, its involvement in …

The rate of melatonin synthesis within pineal glands of female hamsters maintained in an 8-
h light, 16-h dark photoperiod has been calculated. When exposed to these photoperiodic …

Page 1 Melatonin and the Mammalian Pineal Gland Josephine Arendt CHAPMAN & HALL
Page 2 Page 3 54331LVSX00373 Qty: 1 Melatonin and the Mammalian Pineal Page 4 Page 5 …

In 1958, the American dermatologist Aaron Lerner isolated from many thousands of beef
pineal glands the most potent known amphibian skin-lightening factor. This compound was …

I. Pathway for Melatonin Synthesis in Rat Pineal Glands (Fig. 1) M ELATONIN is believed to
be synthesized in the pineal gland from serotonin by a two-step pathway. N …

Circadian production and secretion of melatonin from mammalian pineal gland provides
animals with information concerning the light/dark environment. Melatonin passes easily …

It has been suspected for many years that the mammalian pineal body secretes biologically
active compounds. As early as 1938, investigators demonstrated that minute quantities (3 …

The normal 24 hours patterns of melatonin were described in experimental animals and
man. The rhythms are generated by neuronal activity originating in the suprachiasmatic …

One purpose of this study was to determine if pineal melatonin is altered by chronic
exposure to a lighting schedule which induces gonadal atrophy in the male Syrian hamster …