A research protocol states the rationale, objectives, hypothesis, methodology, source of
funding, institutional affiliations and potential conflicts of interest of a proposed study (Moher …

Well‐designed and properly conducted randomized clinical trials provide a true estimate of
the effects of interventions and are acknowledged as the gold standard in terms of clinical …

In evidence‐based health care, randomized clinical trials provide the most accurate and
reliable information on the effectiveness of an intervention. This project aimed to develop …

Randomized clinical trials are positioned at the highest level of primary clinical evidence, as
they are designed to be unbiased with a reduced risk of systematic error. The Consolidated …

Aim To critically evaluate the reporting quality of a random sample of clinical trials published
in Endodontics against the PRIRATE 2020 checklist and to analyse the association between …

© 2019 John Wiley & Sons A/S and The Gerodontology Association. Published by John
Wiley & Sons Ltd. This is an author-produced version of the published paper. Uploaded in …

Randomized clinical trials are considered the highest quality primary investigative research
study (Centre for Evidence-based Medicine 2009) and are essential to establish the …

Aim To assess the prevalence of registration of clinical trials in endodontic research and to
identify outcome reporting discrepancies between trial registration entries and respective …

Randomized clinical trials are acknowledged as the most appropriate methodology for
demonstrating the efficacy or effectiveness of one intervention as opposed to another and …

Introduction Reports on randomized clinical trials (RCTs) are of critical importance because
readers of research often do not access the full text. This study aimed to assess the reporting …