Involvement of reactive oxygen species in membrane phospholipid breakdown and energy perturbation after traumatic brain injury in the rat

A LEWÉN, L HILLERED - Journal of neurotrauma, 1998 - liebertpub.com
Interstitial glycerol may be a useful marker for posttraumatic and postischemic membrane
phospholipid (PL) breakdown. Degradation of membrane PLs is thought to be triggered by …

Glycerol as a marker for post-traumatic membrane phospholipid degradation in rat brain

N Marklund, K Salci, A Lewén, L Hillered - Neuroreport, 1997 - journals.lww.com
DEGRADATION of membrane phospholipids (PLs) is a well known phenomenon in acute
brain injuries and is thought to underlie the disturbance of vital cellular membrane functions …

Interstitial glycerol as a marker for membrane phospholipid degradation in the acutely injured human brain

L Hillered, J Valtysson, P Enblad… - Journal of Neurology …, 1998 - jnnp.bmj.com
OBJECTIVE Brain interstitial glycerol was studied as a potential marker for membrane
phospholipid degradation in acute human brain injury. METHODS Glycerol was measured …

Validation of brain extracellular glycerol as an indicator of cellular membrane damage due to free radical activity after traumatic brain injury

A Merenda, M Gugliotta, R Holloway… - Journal of …, 2008 - liebertpub.com
Following severe traumatic brain injury (TBI), increasing oxygen delivery to the brain has
been advocated as a useful strategy to reverse mitochondrial dysfunction and improve …

Mitochondrial protection after traumatic brain injury by scavenging lipid peroxyl radicals

AG Mustafa, IN Singh, J Wang… - Journal of …, 2010 - Wiley Online Library
J. Neurochem.(2010) 114, 271–280. Abstract Mitochondrial dysfunction after traumatic brain
injury (TBI) is manifested by increased levels of oxidative damage, loss of respiratory …

Association between elevated brain tissue glycerol levels and poor outcome following severe traumatic brain injury

T Clausen, OL Alves, M Reinert, E Doppenberg… - Journal of …, 2005 - thejns.org
Object. Glycerol is considered to be a marker of cell membrane degradation and thus
cellular lysis. Recently, it has become feasible to measure via microdialysis cerebral …

Delayed phospholipid degradation in rat brain after traumatic brain injury

P Homayoun, EB Rodriguez de Turco… - Journal of …, 1997 - Wiley Online Library
Lipid second messengers such as arachidonic acid and its metabolites and diacylglycerols
(DAGs) are affected in brain injury. Therefore, changes in the pool size and the fatty acid …

Enhanced lipid peroxidation processes in patients after brain contusion

HA Kasprzak, A Woźniak, G Drewa… - Journal of …, 2001 - liebertpub.com
Erythrocyte superoxide dismutase (SOD-1) activity and cerebrospinal fluid (CSF), blood
plasma low-density lipoprotein (LDL) and erythrocyte thiobarbituric acid reactive substance …

Changes of cerebral energy metabolism and lipid peroxidation in rats leading to mitochondrial dysfunction after diffuse brain injury

R VAGNOZZI, A MARMAROU, B TAVAZZI… - Journal of …, 1999 - liebertpub.com
The effect of mild closed head trauma, induced by the weight-drop method (450 g from a 1-m
height), on lipid peroxidation and energy metabolism of brain tissue was determined at …

Changes in free fatty acids, phospholipids, and cholesterol following impact injury to the rat spinal cord

P Demediuk, MP Daly, AI Faden - Journal of neuroscience …, 1989 - Wiley Online Library
Free fatty acids (FFA), phospholipid, and cholesterol levels were measured in spinal cord
samples from rats subjected to low (25 g‐cm), moderate (50 g‐cm), or severe (100 g‐cm) …