Over the last decade animal models have been used extensively to investigate disease
processes and therapy for Helicobacter pylori infections. The H. pylori animal models which …

The acceptance of Helicobacter pylori as a major human pathogen has necessitated the
development of animal models to help elucidate the pathogenic mechanisms of this …

Animal models are essential for in vivo analysis of Helicobacter-related diseases.
Transgenic mice and Mongolian gerbil models have been the corner stone of present …

Animal models are used to study complex host, microbial, and environmental influences
associated with gastric Helicobacter infection. Evidence that gastric helicobacters are …

Following the demonstration of Helicobacter pylori as a major gastroduodenal pathogen
there was a need to develop animal models in order to investigate mechanisms of …

Animal models of microbial diseases in humans are an essential component for determining
fulfillment of Koch's postulates and determining how the organism causes disease, host …

Infection with Helicobacter pylori (H. pylori) is of great distress because of its vital role in the
pathogenesis of chronic gastritis, peptic ulcers, and in the multi-step carcinogenic process of …

Preclinical mouse infection models are widely used for Helicobacter vaccine development,
but how well such models mimic important aspects of human infections is unknown. A …

Presence of Helicobacter pylori in the human gastric mucosa is associated with chronic
gastritis and promotes the formation of peptic ulceration. Furthermore, long-term gastritis …

BACKGROUND & AIMS: Currently available Helicobacter pylori models show variable and,
in some instances, poor colonization. There is a need for a strain with high colonizing ability …