Recently, mitochondria have been identified as important contributors to the virulence and
drug tolerance of human fungal pathogens. In different scenarios, either hypo-or …

The mitochondrion plays wide-ranging roles in eukaryotic cell physiology. In pathogenic
fungi, this central metabolic organelle mediates a range of functions related to disease, from …

In recent years, the role of mitochondria in pathogenic fungi in terms of azole resistance and
fungal pathogenicity has been a rapidly developing field. In this review, we describe the …

Mitochondria are best known for their role in the production of ATP; however, recent
research implicates other mitochondrial functions in the virulence of human pathogenic …

Highlights•Mitochondria play a central role in fungal senescence and quiescence.•
Mitochondria play a key role in fungal virulence, pathogenicity, and drug …

Fungal pathogens threaten human health both directly as infectious agents and indirectly by
limiting crop production, and new approaches are desperately needed to combat fungal …

The frequency of opportunistic fungal infection has increased drastically, mainly in patients
who are immunocompromised due to organ transplant, leukemia or HIV infection. In spite of …

Mitochondria are essential for cell growth and survival of most fungal pathogens. Energy
(ATP) produced during oxidation/reduction reactions of the electron transport chain (ETC) …

The human fungal pathogen Candida albicans requires respiratory function for normal
growth, morphogenesis, and virulence. Mitochondria therefore represent an enticing target …

The respiratory chain has been proposed as an attractive target for the development of new
therapies to tackle human fungal pathogens. This arises from the presence of fungal-specific …