Pathophysiology of intermittent claudication in peripheral artery disease

NM Hamburg, MA Creager - Circulation Journal, 2017 - jstage.jst.go.jp
Peripheral artery disease (PAD) affects more than 200 million adults worldwide. Patients
with lower extremity PAD have a heightened risk for cardiovascular events because of the …

Physiology in medicine: peripheral arterial disease

MD Muller, AB Reed… - Journal of applied …, 2013 - journals.physiology.org
Peripheral arterial disease (PAD) is an atherosclerotic condition that can provoke symptoms
of leg pain (“intermittent claudication”) during exercise. Because PAD is often observed with …

[HTML][HTML] Medical management of peripheral arterial disease

BLW Bendermacher, EM Willigendael… - Journal of Thrombosis …, 2005 - Elsevier
Whether symptomatic or not, peripheral arterial disease (PAD), atherosclerosis in the
arteries of the lower extremities, is a common disorder in the general population. The …

Update on peripheral artery disease: Epidemiology and evidence-based facts

J Shu, G Santulli - Atherosclerosis, 2018 - atherosclerosis-journal.com
Peripheral artery disease (PAD) is a progressive disorder characterized by stenosis and/or
occlusion of large and medium-sized arteries, other than those that supply the heart …

Lower extremity manifestations of peripheral artery disease: the pathophysiologic and functional implications of leg ischemia

MMG McDermott - Circulation research, 2015 - Am Heart Assoc
Lower extremity peripheral artery disease (PAD) is frequently underdiagnosed, in part
because of the wide variety of leg symptoms manifested by patients with PAD and in part …

Clinical trials for claudication: assessment of exercise performance, functional status, and clinical end points

WR Hiatt, AT Hirsch, JG Regensteiner, EP Brass - Circulation, 1995 - Am Heart Assoc
Peripheral arterial disease (PAD) affects a large proportion of the general population, with
an age-adjusted prevalence of approximately 12% and a prevalence of intermittent …

Medical therapy in peripheral artery disease

JS Berger, WR Hiatt - Circulation, 2012 - Am Heart Assoc
The epidemiology of peripheral artery disease (PAD) is well described and related to age
and, in particular, the risk factors of diabetes mellitus and smoking. Recent data from the …

Update on the pathophysiology and medical treatment of peripheral artery disease

J Golledge - Nature Reviews Cardiology, 2022 - nature.com
Approximately 6% of adults worldwide have atherosclerosis and thrombosis of the lower
limb arteries (peripheral artery disease (PAD)) and the prevalence is rising. PAD causes leg …

Medical treatment of peripheral arterial disease: a comprehensive review

A Stoyioglou, MR Jaff - Journal of Vascular and Interventional Radiology, 2004 - Elsevier
Peripheral arterial disease (PAD) is a common manifestation of atherosclerosis that affects
more than 10 million people in the United States. The risk factors associated with PAD are …

Intermittent claudication: an overview

AV Meru, S Mittra, B Thyagarajan, A Chugh - Atherosclerosis, 2006 - Elsevier
Intermittent claudication (IC) is defined by leg muscle pain, cramping and fatigue brought on
by ambulation/exercise; relieved on rest; and caused by inadequate blood supply and is the …