Introduction Medications which target benzodiazepine (BZD) binding sites of GABAA
receptors (GABAARs) have been in widespread use since the nineteen-sixties. They carry …

Background: Diazepam, one of the benzodiazepines, is widely used clinically to treat
anxiety, for termination of epilepsy, and for sedation. However, the reports of its adverse …

GABA A receptor (GABA AR) modulators--notably the benzodiazepines such as diazepam
and alprazolam--are well-established drugs for the treatment of anxiety, epilepsy and other …

Abstract Background and Objective Current methods are not designed to relate the
incidence of individual adverse events reported in clinical trials to the plurality of adverse …

Purpose: Although designer benzodiazepines (DBZDs) constitute a minor part of new
psychoactive substances, they deserve the greatest attention because of their popularity …

Benzodiazepines (BDZs) have been in use since 1960s and are still prescribed at high rates
with over 90 million prescriptions dispensed in the US alone each year (1). In 2015, one in …

Aims Gabapentin and pregabalin bind to α2‐δ subunit of voltage‐gated calcium channels
(Cav). Other drugs targeting Cav include cardiovascular calcium channel blockers (CCBs) …

Purpose Communication atypicalities are considered promising markers of a broad range of
clinical conditions. However, little is known about the mechanisms and confounders …

Benzodiazepines have been in use for over half a century. While they remain highly
prescribed, their unfavorable side-effect profile and abuse liability motivated a search for …

Since the mid 1980's, there has been an increased focus on the side effects of
benzodiazepines (GABA enhancers), and as a result there has been a decrease in their use …