Hot spot 19F magnetic resonance imaging of inflammation

P Bouvain, S Temme, U Flögel - Wiley Interdisciplinary Reviews …, 2020 - Wiley Online Library
Among the preclinical molecular imaging approaches, lately fluorine (19F) magnetic
resonance imaging (MRI) has garnered significant scientific interest in the biomedical …

Visualization of inflammation using 19F‐magnetic resonance imaging and perfluorocarbons

G Stoll, T Basse‐Lüsebrink, G Weise… - Wiley Interdisciplinary …, 2012 - Wiley Online Library
Inflammation plays a central pathophysiological role in a large number of diseases. While
conventional magnetic resonance imaging (MRI) can depict gross tissue alterations due to …

19F magnetic resonance imaging of endogenous macrophages in inflammation

S Temme, F Bönner, J Schrader… - Wiley Interdisciplinary …, 2012 - Wiley Online Library
In this article, we review the use of 19F MRI (magnetic resonance imaging) for in vivo
tracking of monocytes and macrophages in the course of tissue inflammation. Emulsified …

Probing different perfluorocarbons for in vivo inflammation imaging by 19F MRI: image reconstruction, biological half‐lives and sensitivity

C Jacoby, S Temme, F Mayenfels, N Benoit… - NMR in …, 2014 - Wiley Online Library
Inflammatory processes can reliably be assessed by 19F MRI using perfluorocarbons
(PFCs), which is primarily based on the efficient uptake of emulsified PFCs by circulating …

[HTML][HTML] Recent advances in 19Fluorine magnetic resonance imaging with perfluorocarbon emulsions

AH Schmieder, SD Caruthers, J Keupp, SA Wickline… - Engineering, 2015 - Elsevier
The research roots of 19fluorine (19F) magnetic resonance imaging (MRI) date back over 35
years. Over that time span, 1H imaging flourished and was adopted worldwide with an …

Dissociation of 19F and fluorescence signal upon cellular uptake of dual-contrast perfluorocarbon nanoemulsions

P Bouvain, V Flocke, W Krämer, R Schubert… - … Resonance Materials in …, 2019 - Springer
Abstract Objective Perfluorocarbon nanoemulsions (PFCs) tagged with fluorescence dyes
have been intensively used to confirm the in vivo 19 F magnetic resonance imaging (MRI) …

Paramagnetic Fluorinated Nanoemulsions for in vivo F-19 MRI

J Rho, E Stares, SR Adams, D Lister, B Leach… - Molecular imaging and …, 2020 - Springer
Purpose We aim to develop perfluorocarbon-based nanoemulsions with improved sensitivity
for detection of inflammatory macrophages in situ using F-19 MRI. Towards this goal, we …

Targeted, Stimuli-Responsive, and Theranostic 19F Magnetic Resonance Imaging Probes

MH Cho, SH Shin, SH Park… - Bioconjugate …, 2019 - ACS Publications
Unlike conventional 1H magnetic resonance imaging (MRI), 19F MRI features unambiguous
detection of fluorine spins due to negligible background signals. Therefore, it is considered a …

[PDF][PDF] Optimization of perfluorocarbon nanoemulsions for molecular imaging by 19F MRI

C Grapentin, F Mayenfels, S Barnert, R Süss… - …, 2014 - researchgate.net
Tracking fate and function of specific cell types by molecular imaging methods is of great
importance for basic research and holds the potential to be clinically applied for initial …

[HTML][HTML] In vivo clearance of 19F MRI imaging nanocarriers is strongly influenced by nanoparticle ultrastructure

AHJ Staal, K Becker, O Tagit, NK Van Riessen… - Biomaterials, 2020 - Elsevier
Perfluorocarbons hold great promise both as imaging agents, particularly for 19 F MRI, and
in therapy, such as oxygen delivery. 19 F MRI is unique in its ability to unambiguously track …