RA is a progressive inflammatory autoimmune disease with articular and systemic effects. Its
exact cause is unknown, but genetic and environmental factors are contributory. T cells, B …

Recent findings have substantiated the importance of T lymphocytes to the pathogenesis of
rheumatoid arthritis (RA). Here, we review emerging data regarding genetic predisposition …

Rheumatoid arthritis (RA) is an autoimmune disease, characterized by chronic inflammation
and synovial hyperplasia in the joints that ultimately lead to cartilage and bone destruction …

Rheumatoid arthritis (RA) is one of the most common chronic inflammatory syndromes. As
such, RA is often considered the prototype disease for defining both the molecular and …

Rheumatoid arthritis (RA) is a systemic, inflammatory autoimmune disorder that presents as
a symmetric polyarthritis associated with swelling and pain in multiple joints, often initially …

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by inflammation
of the synovial lining (synovitis). The inflammation in the RA joint is associated with and …

Biologic therapies that target pathogenic cytokines such as TNF, IL-1β or IL-6 have greatly
improved the treatment of RA. Unfortunately, not all RA patients respond to current biologic …

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by destruction of
cartilage and bone. The destructive lesions result from both immune responses and non …

Rheumatoid arthritis (RA) is an immune-mediated disease of the joints that is characterized
by chronic inflammation and synovial hyperplasia that eventually lead to cartilage and bone …

The development of an immune response to self antigens drives naive T cells to differentiate
into subsets of CD8+ and CD4+ effector cells including TH1, TH2, cells and the more …