Endothelial glycocalyx as a potential theriapeutic target in organ injuries

RN Cao, L Tang, ZY Xia, R Xia - Chinese medical journal, 2019 - mednexus.org
Objective: The endothelial glycocalyx (eGC) is a dynamic and multicomponent layer of
macromolecules found at the surface of vascular endothelium, which is largely …

[HTML][HTML] Glycocalyx degradation in ischemia-reperfusion injury

Z Abassi, Z Armaly, SN Heyman - The American journal of pathology, 2020 - Elsevier
The glycocalyx is a layer coating the luminal surface of vascular endothelial cells. It is vital
for endothelial function as it participates in microvascular reactivity, endothelium interaction …

A review on the physiological and pathophysiological role of endothelial glycocalyx

H Liu, J Li, C Xuan, H Ma - Journal of biochemical and …, 2020 - Wiley Online Library
The glycocalyx is a gel‐like layer covering the luminal surface of vascular endothelial cells. It
comprises of membrane‐attached proteoglycans, glycosaminoglycan chains, glycoproteins …

Targeting the endothelial glycocalyx in acute critical illness as a challenge for clinical and laboratory medicine

V Cerny, D Astapenko, F Brettner, J Benes… - Critical Reviews in …, 2017 - Taylor & Francis
The purpose of this manuscript is to review the role of endothelial glycocalyx (EG) in the field
of critical and perioperative medicine and to discuss possible future directions for …

[HTML][HTML] The endothelial glycocalyx and its disruption, protection and regeneration: a narrative review

U Schött, C Solomon, D Fries, P Bentzer - Scandinavian journal of trauma …, 2016 - Springer
The glycocalyx is a carbohydrate-rich layer that lines the luminal side of the vascular
endothelium. Its soluble components exist in a dynamic equilibrium with the bloodstream …

The endothelial glycocalyx: new diagnostic and therapeutic approaches in sepsis

L Martin, P Koczera, E Zechendorf… - BioMed research …, 2016 - Wiley Online Library
Sepsis is defined as a life‐threatening organ dysfunction caused by a dysregulated host
response to infection. The endothelial glycocalyx is one of the earliest sites involved during …

[HTML][HTML] Endothelial glycocalyx degradation in critical illness and injury

EK Patterson, G Cepinskas, DD Fraser - Frontiers in medicine, 2022 - frontiersin.org
The endothelial glycocalyx is a gel-like layer on the luminal side of blood vessels that is
composed of glycosaminoglycans and the proteins that tether them to the plasma …

[HTML][HTML] Form follows function: the endothelial glycocalyx

A Suzuki, H Tomita, H Okada - Translational Research, 2022 - Elsevier
Three types of capillaries, namely continuous, fenestrated, and sinusoidal, form the
microvascular system; each type has a specialized structure and function to respond to the …

[HTML][HTML] Protection and rebuilding of the endothelial glycocalyx in sepsis–Science or fiction?

CC Drost, A Rovas, P Kümpers - Matrix Biology Plus, 2021 - Elsevier
The endothelial glycocalyx (eGC), a delicate carbohydrate-rich structure lining the luminal
surface of the vascular endothelium, is vital for maintenance of microvascular homeostasis …

Endothelial glycocalyx

J Jedlicka, BF Becker, D Chappell - Critical Care Clinics, 2020 - criticalcare.theclinics.com
The endothelial glycocalyx (EG) is the most luminal layer of the blood vessel, growing on
and within the vascular wall. It is mainly composed of a variety of proteoglycans and …