Effect of cerebral small vessel disease on the integrity of cholinergic system in mild cognitive impairment patients: a longitudinal study

T Qiu, H Hong, Q Zeng, X Xu, Y Wang, L Zhu… - Journal of …, 2024 - Springer
We aimed to investigate the effect of cerebral small vessel disease (SVD) on cholinergic
system integrity in mild cognitive impairment (MCI) patients. Nucleus basalis of Meynert …

Effect of cholinergic pathway disruption on cortical and subcortical volumes in subcortical vascular cognitive impairment

JS Lim, HM Kwon, YS Lee - European Journal of Neurology, 2020 - Wiley Online Library
Background and purpose The brain's cholinergic network has various interconnections with
the cortical and subcortical structures. Disruption of cholinergic pathways by white matter …

[HTML][HTML] The influence of cerebral small vessel disease on default mode network deactivation in mild cognitive impairment

JM Papma, T den Heijer, I de Koning… - NeuroImage: Clinical, 2013 - Elsevier
Introduction Cerebral small vessel disease (CSVD) is thought to contribute to cognitive
dysfunction in patients with mild cognitive impairment (MCI). The underlying mechanisms …

Cerebral small vessel disease affects white matter microstructure in mild cognitive impairment

JM Papma, M de Groot, I de Koning… - Human brain …, 2014 - Wiley Online Library
Microstructural white matter deterioration is a frequent finding in mild cognitive impairment
(MCI), potentially underlying default mode network (DMN) dysfunctioning. Thus far …

Distinctive and pervasive alterations of functional brain networks in cerebral small vessel disease with and without cognitive impairment

R Liu, W Wu, Q Ye, Y Gu, J Zou, X Chen… - Dementia and geriatric …, 2019 - karger.com
Objective: To explore the within-and between-network patterns of the default mode network
(DMN), the frontoparietal control network (FPCN), and the dorsal attention network (DAN) in …

Structural brain network disruption at preclinical stage of cognitive impairment due to cerebral small vessel disease

J Du, H Zhu, J Zhou, P Lu, Y Qiu, L Yu, W Cao, N Zhi… - Neuroscience, 2020 - Elsevier
Cerebral small vessel disease (CSVD) is a common disease among elderly individuals and
recognized as a major cause of vascular cognitive impairment. Recent studies demonstrated …

The effect of ischemic cholinergic damage on cognition in patients with subcortical vascular cognitive impairment

SH Kim, HS Kang, HJ Kim, Y Moon… - Journal of geriatric …, 2012 - journals.sagepub.com
Prior research has shown that the total amount of white matter ischemia had no significant
correlation with cognitive deficits. We compared the association of white matter …

Microstructural changes in the cingulate gyrus of patients with mild cognitive impairment induced by cerebral small vessel disease

H Liu, D Liu, K Li, X Xue, X Ma, Q Bu, J Ma… - Neurological …, 2021 - Taylor & Francis
Objective: The purpose of our study was to distinguish the changes in the microstructure of
the cingulate cortex in patients with mild cognitive impairment (MCI) induced by cerebral …

Clinical study of central cholinergic pathway damage in two mild cognitive impairment patients

Q Liu, M Zhong, S Yuan, C Niu, X Ma - Neurological Sciences, 2021 - Springer
Objectives To explore the role of the central cholinergic system in amnestic mild cognitive
impairment (aMCI) and mild vascular cognitive impairment (vMCI). Methods Twenty-five …

[HTML][HTML] Degeneration of cholinergic white matter pathways and nucleus basalis of Meynert in individuals with objective subtle cognitive impairment

T Qiu, H Hong, Q Zeng, X Luo, X Wang, X Xu, F Xie… - Neurobiology of …, 2023 - Elsevier
We evaluated alterations in the nucleus basalis of Meynert (NBM) volume and integrity of
cholinergic white matter pathways in objective subtle cognitive impairment (Obj-SCI) …