Integrin β1 is an essential factor in vasculogenic mimicry of human cancer cells

R Kawahara, Y Niwa, S Simizu - Cancer science, 2018 - Wiley Online Library
Vasculogenic mimicry (VM) formation by cancer cells is known to play a crucial role in tumor
progression, but its detailed mechanism is unclear. In the present study, we focused on …

Featured Article: Downregulation of transgelin blocks interleukin-8 utilization and suppresses vasculogenic mimicry in breast cancer cells

AR Aikins, MJ Kim, B Raymundo… - … Biology and Medicine, 2017 - journals.sagepub.com
Vasculogenic mimicry (VM) is a non-classical mechanism recently described in many
tumors, whereby cancer cells, rather than endothelial cells, form blood vessels. Transgelin is …

[HTML][HTML] Methionine aminopeptidase‑2 is a pivotal regulator of vasculogenic mimicry

S Shimizu, R Kawahara, S Simizu - Oncology reports, 2022 - spandidos-publications.com
Vasculogenic mimicry (VM) is the formation of a blood supply system that confers aggressive
and metastatic properties to tumors and correlates with a poor prognosis in cancer patients …

Advanced research on vasculogenic mimicry in cancer

L Qiao, N Liang, J Zhang, J Xie, F Liu… - Journal of cellular …, 2015 - Wiley Online Library
Vasculogenic mimicry (VM) is a brand‐new tumour vascular paradigm independent of
angiogenesis that describes the specific capacity of aggressive cancer cells to form vessel …

IGFBP2 promotes vasculogenic mimicry formation via regulating CD144 and MMP2 expression in glioma

Y Liu, F Li, YT Yang, XD Xu, JS Chen, TL Chen… - Oncogene, 2019 - nature.com
Vasculogenic mimicry (VM) refers to the fluid-conducting channels formed by aggressive
tumor cells rather than endothelial cells (EC) with elevated expression of genes associated …

[HTML][HTML] MicroRNA 34A–AXL axis regulates vasculogenic mimicry formation in breast cancer cells

D Lim, JG Cho, E Yun, A Lee, HY Ryu, YJ Lee, S Yoon… - Genes, 2020 - mdpi.com
Targeting the tumor vasculature is an attractive strategy for cancer treatment. However, the
tumor vasculature is heterogeneous, and the mechanisms involved in the …

Overview of advances in vasculogenic mimicry–a potential target for tumor therapy

H Ge, H Luo - Cancer management and research, 2018 - Taylor & Francis
Vasculogenic mimicry (VM) describes the process utilized by highly aggressive cancer cells
to generate vascular-like structures without the presence of endothelial cells. VM has been …

[HTML][HTML] Vasculogenic mimicry in carcinogenesis and clinical applications

Q Luo, J Wang, W Zhao, Z Peng, X Liu, B Li… - Journal of hematology & …, 2020 - Springer
Distinct from classical tumor angiogenesis, vasculogenic mimicry (VM) provides a blood
supply for tumor cells independent of endothelial cells. VM has two distinct types, namely …

[HTML][HTML] Tenascin-c mediated vasculogenic mimicry formation via regulation of MMP2/MMP9 in glioma

H Cai, J Wang, S Xi, X Ni, Y Chen, Y Yu, Z Cen… - Cell Death & …, 2019 - nature.com
Vasculogenic mimicry (VM), the formation of vessel-like structures by highly invasive tumor
cells, has been considered one of several mechanisms responsible for the failure of anti …

[HTML][HTML] IL-1β promotes vasculogenic mimicry of breast cancer cells through p38/MAPK and PI3K/Akt signaling pathways

MA Nisar, Q Zheng, MZ Saleem, B Ahmmed… - Frontiers in …, 2021 - frontiersin.org
Vasculogenic mimicry (VM), a micro vessel-like structure formed by the cancer cells, plays a
pivotal role in cancer malignancy and progression. Interleukin-1 beta (IL-1β) is an active pro …