The pathophysiology of vascular disease is linked to accelerated biological aging and a
combination of genetic, lifestyle, biological, and environmental risk factors. Within the …

Aging is the progressive decline of body functions and a number of chronic conditions can
lead to premature aging characterized by frailty, a diseased vasculature, osteoporosis, and …

Cardiovascular diseases (CVDs), especially those involving a systemic inflammatory
process such as atherosclerosis, remain the leading cause of morbidity and mortality in …

As human life expectancy keeps increasing, ageing populations present a growing
challenge for clinical practices. Human ageing is associated with molecular, structural, and …

Aging is both a natural and inevitable biological process. With advancing age, the kidneys
undergo anatomical and physiological changes that are not only the consequences of …

Renal aging, by itself, is associated with alterations in renal morphology and a decline in
renal function, which is accelerated and/or accentuated by diseases such as diabetes …

Chronic kidney disease (CKD) shares many phenotypic similarities with other chronic
diseases, including heart failure, chronic obstructive pulmonary disease, HIV infection and …

Degenerative diseases, encompassing a wide range of conditions affecting various organ
systems, pose significant challenges to global healthcare systems. This comprehensive …

The rapid growth of the elderly population is making the need for extensive and advanced
information about age-related organ dysfunction a crucial research area. The kidney is one …

Epidemiologic, clinical, and molecular evidence suggest that aging is a major contributor to
the increasing incidence of acute kidney injury and chronic kidney disease. The aging …