General aspects of two-component regulatory circuits in bacteria: domains, signals and roles
F Padilla-Vaca, V Mondragon-Jaimes… - Current Protein and …, 2017 - ingentaconnect.com
All living organisms are subject to changing environments, which must be sensed in order to
respond swiftly and efficiently. Two-component systems (TCS) are signal transduction …
respond swiftly and efficiently. Two-component systems (TCS) are signal transduction …
[HTML][HTML] The mechanism of action of inhibitors of bacterial two-component signal transduction systems
K Stephenson, Y Yamaguchi, JA Hoch - Journal of Biological Chemistry, 2000 - ASBMB
Two-component signal transduction systems allow bacteria to sense and respond rapidly to
changes in their environment leading to specific gene activation or repression. These two …
changes in their environment leading to specific gene activation or repression. These two …
Molecular mechanisms of two-component signal transduction
CP Zschiedrich, V Keidel, H Szurmant - Journal of molecular biology, 2016 - Elsevier
Two-component systems (TCS) comprising sensor histidine kinases and response regulator
proteins are among the most important players in bacterial and archaeal signal transduction …
proteins are among the most important players in bacterial and archaeal signal transduction …
To∼ P or Not to∼ P? Non‐canonical activation by two‐component response regulators
Bacteria sense and respond to their environment through the use of two‐component
regulatory systems. The ability to adapt to a wide range of environmental stresses is directly …
regulatory systems. The ability to adapt to a wide range of environmental stresses is directly …
Organization and mode of action of two component system signaling circuits from the various kingdoms of life
AF Alvarez, C Barba‐Ostria… - Environmental …, 2016 - Wiley Online Library
Two‐component system (TCS) signaling circuits regulate numerous cellular processes in
response to environmental cues in both prokaryotic and eukaryotic cells. These signaling …
response to environmental cues in both prokaryotic and eukaryotic cells. These signaling …
Two-Component Signal Transduction Systems: A Key to the Adaptative Potential of Pseudomonas Aeruginosa
I Ventre, A Filloux, A Lazdunski - Virulence and Gene Regulation, 2004 - Springer
The survival ofbacteria depends on constant sensing oftheir environment and adapting to
changes, these processes require signal transduction across biological membranes. A …
changes, these processes require signal transduction across biological membranes. A …
[HTML][HTML] Two-component signal transduction
RB Bourret, RE Silversmith - Current opinion in microbiology, 2010 - ncbi.nlm.nih.gov
Department of Microbiology & Immunology, University of North Carolina, Chapel Hill, NC
27599-7290, USA silversr@ med. unc. edu 1986 was a very good year for research on …
27599-7290, USA silversr@ med. unc. edu 1986 was a very good year for research on …
Signal integration in bacterial two-component regulatory systems
AY Mitrophanov, EA Groisman - Genes & development, 2008 - genesdev.cshlp.org
Two-component systems (TCSs) and phosphorelays are key mediators of bacterial signal
transduction. The signals activating these systems promote the phosphorylated state of a …
transduction. The signals activating these systems promote the phosphorylated state of a …
[HTML][HTML] Progress overview of bacterial two-component regulatory systems as potential targets for antimicrobial chemotherapy
H Hirakawa, J Kurushima, Y Hashimoto, H Tomita - Antibiotics, 2020 - mdpi.com
Bacteria adapt to changes in their environment using a mechanism known as the two-
component regulatory system (TCS)(also called “two-component signal transduction system” …
component regulatory system (TCS)(also called “two-component signal transduction system” …
[HTML][HTML] Two-component signal transduction systems of pathogenic bacteria as targets for antimicrobial therapy: an overview
The bacterial communities in a wide range of environmental niches sense and respond to
numerous external stimuli for their survival. Primarily, a source they require to follow up this …
numerous external stimuli for their survival. Primarily, a source they require to follow up this …