Flavonoid compounds have anti-diabetic activity, which can control blood glucose levels by
inhibiting α-glucosidase activity. In this paper, the inhibition mechanisms between four …

Biflavonoids are a kind of polyphenol compounds with numerous biological functions.
However, the potential inhibitory activities of biflavonoids on α-glucosidase are yet unknown …

Flavonoids are known to play a role in hypoglycemia by inhibiting α-glucosidase. However,
their interaction mechanism with α-glucosidase still needs to be elaborated. In this study, the …

The inhibition of α-glucosidase activity is a prospective approach to prevent postprandial
hyperglycemia. As two flavonoids extracted from citrus fruits, eriocitrin and eriodictyol have …

Epimedium brevicornum leaves water extract exerted a potent and specific inhibition against
yeast α-glucosidase, with 50% inhibition of activity (IC50) at 11.8 μmol/L (or 2.01 μg) Gallic …

Abstract α-Glucosidase is a therapeutic target for diabetes mellitus, and α-glucosidase
inhibitors play a vital role in the treatments for the disease. As a kind of potentially safer α …

Inhibition of α-glucosidase activity may suppress postprandial hyperglycemia. The inhibition
kinetic analysis showed that apigenin reversibly inhibited α-glucosidase activity with an IC50 …

Tartary buckwheat has been shown to provide a good antihyperglycemic effect. However, it
is unclear which active compounds play a key role in attenuating postprandial …

The structure–activity relationship and inhibitory mechanism of flavonols on α-glucosidase
were studied by inhibition kinetics, multispectral study, and molecular docking. The flavonols …

Three flavonoids from tartary buckwheat bran, namely, quercetin (Que), isoquercetin (Iso)
and rutin (Rut), have been evaluated as α-glucosidase inhibitors by fluorescence …