How I treat unique and difficult-to-manage cases of CAR T-cell therapy–associated neurotoxicity
With growing indications for chimeric antigen receptor (CAR) T-cell therapy, toxicity profiles
are evolving. There is an urgent and unmet need of approaches to optimally manage …
are evolving. There is an urgent and unmet need of approaches to optimally manage …
How I treat refractory CRS and ICANS after CAR T-cell therapy
MD Jain, M Smith, NN Shah - … Journal of the American Society of …, 2023 - ashpublications.org
The clinical use of chimeric antigen receptor (CAR) T-cell therapy is growing rapidly
because of the expanding indications for standard-of-care treatment and the development of …
because of the expanding indications for standard-of-care treatment and the development of …
Neurological updates: neurological complications of CAR-T therapy
EC Tallantyre, NA Evans, J Parry-Jones… - Journal of …, 2021 - Springer
Chimeric antigen receptor (CAR)-expressing T cells now offer an effective treatment option
for people with previously refractory B cell malignancies and are under development for a …
for people with previously refractory B cell malignancies and are under development for a …
Immune effector cell associated neurotoxicity syndrome in chimeric antigen receptor-T cell therapy
RC Sterner, RM Sterner - Frontiers in immunology, 2022 - frontiersin.org
Chimeric antigen receptor (CAR)-T cell therapy is an emerging staple in the treatment of
certain hematological malignancies. While CAR-T cells have produced robust responses in …
certain hematological malignancies. While CAR-T cells have produced robust responses in …
Complete spectrum of adverse events associated with chimeric antigen receptor (CAR)-T cell therapies
Chimeric antigen receptor (CAR)-T cell therapies have been approved by FDA to treat
relapsed or refractory hematological malignancies. However, the adverse effects of CAR-T …
relapsed or refractory hematological malignancies. However, the adverse effects of CAR-T …
In the eye of the storm: immune-mediated toxicities associated with CAR-T cell therapy
JG Borrega, P Gödel, MA Rüger, ÖA Onur… - …, 2019 - journals.lww.com
The success of chimeric antigen receptor (CAR)-T cell therapy with impressive response
rates in hematologic malignancies but also promising data in solid tumors came along with …
rates in hematologic malignancies but also promising data in solid tumors came along with …
Clinical presentation, risk factors, and outcomes of immune effector cell-associated neurotoxicity syndrome following chimeric antigen receptor T cell therapy: a …
SJ Grant, AA Grimshaw, J Silberstein… - … and cellular therapy, 2022 - Elsevier
Chimeric antigen receptor (CAR) T cell therapy is a novel therapy for patients with relapsed
or refractory hematologic malignancies. Most CAR T cell therapy recipients will experience …
or refractory hematologic malignancies. Most CAR T cell therapy recipients will experience …
Neurotoxicity—CAR T-cell therapy: what the neurologist needs to know
L Neill, J Rees, C Roddie - Practical Neurology, 2020 - pn.bmj.com
Chimeric antigen receptor (CAR) T-cell therapy is one of the most innovative therapies for
haematological malignancies to emerge in a generation. Clinical studies have shown that a …
haematological malignancies to emerge in a generation. Clinical studies have shown that a …
Neurological adverse effects of chimeric antigen receptor T-cell therapy
K Saleki, MH Mohamadi, P Alijanizadeh… - Expert Review of …, 2023 - Taylor & Francis
Introduction Chimeric antigen receptor (CAR) T-cell is among the most prevalent
approaches that act by directing T-cells toward cancer; however, they need to be optimized …
approaches that act by directing T-cells toward cancer; however, they need to be optimized …
CAR T-cell-associated neurotoxicity in central nervous system hematologic disease: Is it still a concern?
R Velasco, A Mussetti, M Villagrán-García… - Frontiers in …, 2023 - frontiersin.org
Chimeric antigen receptor (CAR) T-cell systemic immunotherapy has revolutionized how
clinicians treat several refractory and relapsed hematologic malignancies. Due to its peculiar …
clinicians treat several refractory and relapsed hematologic malignancies. Due to its peculiar …