Bioactive Iridium Nanoclusters with Glutathione Depletion Ability for Enhanced Sonodynamic‐Triggered Ferroptosis‐Like Cancer Cell Death

T Nie, W Zou, Z Meng, L Wang, T Ying, X Cai… - Advanced …, 2022 - Wiley Online Library
Ferroptosis is a regulated form of necrotic cell death that involves the accumulation of lipid
peroxide (LPO) species in an iron‐and reactive oxygen species (ROS)‐dependent manner …

Targeting ferroptosis synergistically sensitizes apoptotic sonodynamic anti-tumor nanotherapy

L Zhou, C Dong, L Ding, W Feng, L Yu, X Cui, Y Chen - Nano Today, 2021 - Elsevier
Nanosensitizer-enabled sonodynamic therapy (SDT) represents an appealing anti-tumor
modality to induce apoptotic cancer-cell death by generating highly toxic reactive oxygen …

Ultrasound‐augmented nanocatalytic ferroptosis reverses chemotherapeutic resistance and induces synergistic tumor nanotherapy

Y Zheng, X Li, C Dong, L Ding, H Huang… - Advanced Functional …, 2022 - Wiley Online Library
Inducing ferroptosis has been acknowledged as an emerging strategy to kill drug‐resistant
tumor cells, but how to efficiently induce ferroptosis at the tumor site and enhance its …

A self-amplifying nanodrug to manipulate the Janus-faced nature of ferroptosis for tumor therapy

M Zhang, X Qin, Z Zhao, Q Du, Q Li, Y Jiang… - Nanoscale …, 2022 - pubs.rsc.org
Ferroptosis, an unusual non-apoptotic cell death caused by the iron-dependent
accumulation of lipid peroxide, enables the flexible design of an antitumor platform …

Radiotherapy-mediated redox homeostasis-controllable nanomedicine for enhanced ferroptosis sensitivity in tumor therapy

Y Lin, X Chen, C Yu, G Xu, X Nie, Y Cheng, Y Luan… - Acta Biomaterialia, 2023 - Elsevier
Ferroptosis has received increasing attentions in cancer therapy owing to its unique
advantages over apoptosis. However, ferroptosis is governed by the efficiency of reactive …

[HTML][HTML] Induction of ferroptosis using functionalized iron-based nanoparticles for anti-cancer therapy

C Bae, H Kim, YM Kook, C Lee, C Kim, C Yang… - Materials Today Bio, 2022 - Elsevier
Ferroptosis, a cell death pathway that is induced in response to iron, has recently attracted
remarkable attention given its emerging therapeutic potential in cancer cells. The need for a …

Oxidative stress-amplified nanomedicine for intensified ferroptosis-apoptosis combined tumor therapy

M Yu, J Yu, Y Yi, T Chen, L Yu, W Zeng… - Journal of Controlled …, 2022 - Elsevier
Ferroptosis, as an effective sensitizer for apoptosis-based cancer treatments, has been
elucidated to rely on high levels of intracellular oxidative stress mediated by the …

Acidity‐activatable dynamic nanoparticles boosting ferroptotic cell death for immunotherapy of cancer

R Song, T Li, J Ye, F Sun, B Hou, M Saeed… - Advanced …, 2021 - Wiley Online Library
Immunotherapy shows promising therapeutic potential for long‐term tumor regression.
However, current cancer immunotherapy displays a low response rate due to insufficient …

[HTML][HTML] Metal ions/nucleotide coordinated nanoparticles comprehensively suppress tumor by synergizing ferroptosis with energy metabolism interference

Y Wang, J Chen, J Lu, J Xi, Z Xu, L Fan, H Dai… - Journal of …, 2022 - Springer
Background Ferroptosis holds promise as a potential tumor therapy by programming cell
death with a hallmark of reactive oxygen species (ROS)-induced lipid peroxidation …

Arginine-rich manganese silicate nanobubbles as a ferroptosis-inducing agent for tumor-targeted theranostics

S Wang, F Li, R Qiao, X Hu, H Liao, L Chen, J Wu… - ACS …, 2018 - ACS Publications
Ferroptosis, an iron-based cell-death pathway, has recently attracted great attention owing
to its effectiveness in killing cancer cells. Previous investigations focused on the …