Bioactive Iridium Nanoclusters with Glutathione Depletion Ability for Enhanced Sonodynamic‐Triggered Ferroptosis‐Like Cancer Cell Death
T Nie, W Zou, Z Meng, L Wang, T Ying, X Cai… - Advanced …, 2022 - Wiley Online Library
Ferroptosis is a regulated form of necrotic cell death that involves the accumulation of lipid
peroxide (LPO) species in an iron‐and reactive oxygen species (ROS)‐dependent manner …
peroxide (LPO) species in an iron‐and reactive oxygen species (ROS)‐dependent manner …
Targeting ferroptosis synergistically sensitizes apoptotic sonodynamic anti-tumor nanotherapy
Nanosensitizer-enabled sonodynamic therapy (SDT) represents an appealing anti-tumor
modality to induce apoptotic cancer-cell death by generating highly toxic reactive oxygen …
modality to induce apoptotic cancer-cell death by generating highly toxic reactive oxygen …
Ultrasound‐augmented nanocatalytic ferroptosis reverses chemotherapeutic resistance and induces synergistic tumor nanotherapy
Y Zheng, X Li, C Dong, L Ding, H Huang… - Advanced Functional …, 2022 - Wiley Online Library
Inducing ferroptosis has been acknowledged as an emerging strategy to kill drug‐resistant
tumor cells, but how to efficiently induce ferroptosis at the tumor site and enhance its …
tumor cells, but how to efficiently induce ferroptosis at the tumor site and enhance its …
A self-amplifying nanodrug to manipulate the Janus-faced nature of ferroptosis for tumor therapy
M Zhang, X Qin, Z Zhao, Q Du, Q Li, Y Jiang… - Nanoscale …, 2022 - pubs.rsc.org
Ferroptosis, an unusual non-apoptotic cell death caused by the iron-dependent
accumulation of lipid peroxide, enables the flexible design of an antitumor platform …
accumulation of lipid peroxide, enables the flexible design of an antitumor platform …
Radiotherapy-mediated redox homeostasis-controllable nanomedicine for enhanced ferroptosis sensitivity in tumor therapy
Y Lin, X Chen, C Yu, G Xu, X Nie, Y Cheng, Y Luan… - Acta Biomaterialia, 2023 - Elsevier
Ferroptosis has received increasing attentions in cancer therapy owing to its unique
advantages over apoptosis. However, ferroptosis is governed by the efficiency of reactive …
advantages over apoptosis. However, ferroptosis is governed by the efficiency of reactive …
[HTML][HTML] Induction of ferroptosis using functionalized iron-based nanoparticles for anti-cancer therapy
Ferroptosis, a cell death pathway that is induced in response to iron, has recently attracted
remarkable attention given its emerging therapeutic potential in cancer cells. The need for a …
remarkable attention given its emerging therapeutic potential in cancer cells. The need for a …
Oxidative stress-amplified nanomedicine for intensified ferroptosis-apoptosis combined tumor therapy
M Yu, J Yu, Y Yi, T Chen, L Yu, W Zeng… - Journal of Controlled …, 2022 - Elsevier
Ferroptosis, as an effective sensitizer for apoptosis-based cancer treatments, has been
elucidated to rely on high levels of intracellular oxidative stress mediated by the …
elucidated to rely on high levels of intracellular oxidative stress mediated by the …
Acidity‐activatable dynamic nanoparticles boosting ferroptotic cell death for immunotherapy of cancer
R Song, T Li, J Ye, F Sun, B Hou, M Saeed… - Advanced …, 2021 - Wiley Online Library
Immunotherapy shows promising therapeutic potential for long‐term tumor regression.
However, current cancer immunotherapy displays a low response rate due to insufficient …
However, current cancer immunotherapy displays a low response rate due to insufficient …
[HTML][HTML] Metal ions/nucleotide coordinated nanoparticles comprehensively suppress tumor by synergizing ferroptosis with energy metabolism interference
Y Wang, J Chen, J Lu, J Xi, Z Xu, L Fan, H Dai… - Journal of …, 2022 - Springer
Background Ferroptosis holds promise as a potential tumor therapy by programming cell
death with a hallmark of reactive oxygen species (ROS)-induced lipid peroxidation …
death with a hallmark of reactive oxygen species (ROS)-induced lipid peroxidation …
Arginine-rich manganese silicate nanobubbles as a ferroptosis-inducing agent for tumor-targeted theranostics
Ferroptosis, an iron-based cell-death pathway, has recently attracted great attention owing
to its effectiveness in killing cancer cells. Previous investigations focused on the …
to its effectiveness in killing cancer cells. Previous investigations focused on the …