Point-of-care diagnostics to improve maternal and neonatal health in low-resource settings

CE Majors, CA Smith, ME Natoli, KA Kundrod… - Lab on a Chip, 2017 - pubs.rsc.org
Each day, approximately 830 women and 7400 newborns die from complications during
pregnancy and childbirth. Improving maternal and neonatal health will require bringing rapid …

[HTML][HTML] A rapid smartphone-based lactate dehydrogenase test for neonatal diagnostics at the point of care

CP Halvorsen, L Olson, AC Araújo, M Karlsson… - Scientific Reports, 2019 - nature.com
There is a growing recognition of the importance of point-of-care tests (POCTs) for detecting
critical neonatal illnesses to reduce the mortality rate in newborns, especially in low-income …

Neonatal point-of-care testing

T Naghdi, AR Sharifi, RS Tabatabaee, E Azizi… - TrAC Trends in …, 2024 - Elsevier
More than 6,000 infant deaths every day in just the first month of life is a severe alarm for
healthcare systems on the eve of Healthcare 5.0. By providing timely, reliable, yet affordable …

[HTML][HTML] Causes of death identified in neonates enrolled through Child Health and Mortality Prevention Surveillance (CHAMPS), December 2016–December 2021

S Mahtab, SA Madhi, VL Baillie, T Els… - PLOS Global Public …, 2023 - journals.plos.org
Each year, 2.4 million children die within their first month of life. Child Health and Mortality
Prevention Surveillance (CHAMPS) established in 7 countries aims to generate accurate …

Advancing human health in the decade ahead: pregnancy as a key window for discovery: a Burroughs Wellcome Fund Pregnancy Think Tank

Y Sadovsky, S Mesiano, GJ Burton, M Lampl… - American journal of …, 2020 - Elsevier
Recent revolutionary advances at the intersection of medicine, omics, data sciences,
computing, epidemiology, and related technologies inspire us to ponder their impact on …

[HTML][HTML] Tracking facility-based perinatal deaths in Tanzania: Results from an indicator validation assessment

M Plotkin, D Bishanga, H Kidanto, MC Jennings… - PloS one, 2018 - journals.plos.org
Background Globally, an estimated 2.7 million babies die in the neonatal period annually,
and of these, about 0.7 million die from intrapartum-related events. In Tanzania 51,000 …

[HTML][HTML] Categorising interventions to levels of inpatient care for small and sick newborns: Findings from a global survey

SG Moxon, H Blencowe, P Bailey, J Bradley, LT Day… - PLoS …, 2019 - journals.plos.org
Background In 2017, 2.5 million newborns died, mainly from prematurity, infections, and
intrapartum events. Preventing these deaths requires health systems to provide routine and …

Facility-based identification of women with severe maternal morbidity: it is time to start

WM Callaghan, WA Grobman, SJ Kilpatrick… - Obstetrics & …, 2014 - journals.lww.com
Although maternal deaths have been the traditional indicator of maternal health, these
events are the “tip of the iceberg” in that there are many women who have significant …

[HTML][HTML] A framework for key considerations regarding point-of-care screening of newborns

AR Kemper, CA Kus, RJ Ostrander, AM Comeau… - Genetics in …, 2012 - nature.com
Newborn screening is performed under public health authority, with analysis carried out
primarily by public health laboratories or other centralized laboratories. Increasingly …

[HTML][HTML] Estimating baseline rates of adverse perinatal and neonatal outcomes using a facility-based surveillance approach: A prospective observational study from …

A Sharan, AL Stuurman, S Jahagirdar, V Elango… - …, 2022 - thelancet.com
Background Most perinatal and neonatal deaths occur in low-and middle-income countries
(LMICs), yet, quality data on burden of adverse outcomes of pregnancy is limited in such …