G-Quadruplexes (GQs) serve as popular recognition elements for DNA aptasensors and are
incorporated into a DNA nanodevice capable of controlled conformational changes to …

G-tetrads are essential structural components required for the formation of G-quadruplexes.
Replacement of G nucleobases within G-tetrads with fluorescent 8-aryl-dG residues …

G-quadruplexes constitute an important type of nucleic acid structure, which can be found in
living cells and applied by cell machinery as pivotal regulatory elements. Importantly, robust …

In order to expand the potential applications of G‐quadruplex structures, we explored the
ability of heterochiral oligodeoxynucleotides based on the thrombin‐binding aptamer (TBA) …

Kinetically grafting G-quadruplexes onto one-dimensional DNA nanostructures with precise
positioning was realized in this study. The programs hold great promise for label-free and …

Highly specific and tight-binding nucleic acid aptamers have been selected against a variety
of molecular targets for over 20 years. A significant proportion of these oligonucleotides …

A DNA aptazyme consists of an aptamer domain and a DNAzyme module, in which the
DNAzyme activity can be regulated by the aptamer–target interaction. The complex of G …

Fluorescent nucleobases represent an important class of molecular reporters of nucleic acid
interactions. In this work, the advantages of utilizing a noncanonical fluorescent nucleobase …

Guanine‐rich DNA sequences are able to form G‐quadruplexes, being involved in important
biological processes and representing smart self‐assembling nanomaterials that are …

We describe the single-molecule sensing of G-quadruplex (Gq) formation in target-bound
aptamers using solid-state nanopores. In order to do this, we functionalize the solid-state …