[HTML][HTML] Preventive and therapeutic role of Tanshinone ⅡA in hepatology

MJ Shi, BS Dong, WN Yang, SB Su, H Zhang - Biomedicine & …, 2019 - Elsevier
Liver diseases cause serious public health problems because of their high global
prevalence and poor long-term clinical outcomes. With its mild and broad therapeutic …

[HTML][HTML] Tanshinone IIA and hepatocellular carcinoma: A potential therapeutic drug

H Li, P Hu, Y Zou, L Yuan, Y Xu, X Zhang, X Luo… - Frontiers in …, 2023 - frontiersin.org
Because of its high prevalence and poor long-term clinical treatment effect, liver disease is
regarded as a major public health problem around the world. Among them, viral hepatitis …

Therapeutic effect of tanshinone IIA on liver fibrosis and the possible mechanism: a preclinical meta‐analysis

Q Ying, Y Teng, J Zhang, Z Cai… - … and Alternative Medicine, 2019 - Wiley Online Library
Background. Liver fibrosis is a serious human health problem, and there is a need for
specific antifibrosis drugs in the clinic. Tanshinone IIA has recently been reported to have a …

Pharmacological activity and mechanism of tanshinone IIA in related diseases

R Guo, L Li, J Su, S Li, SE Duncan, Z Liu… - Drug Design …, 2020 - Taylor & Francis
Salvia miltiorrhiza:(Danshen) is a significant (traditional Chinese medication) natural
remedy, enhancing blood circulation and clear blood stasis. In this view, it is widely used …

Tanshinone IIA ameliorates nonalcoholic steatohepatitis in mice by modulating neutrophil extracellular traps and hepatocyte apoptosis

L Xu, X Liu, T Jia, Y Sun, Y Du, S Wei… - Evidence‐Based …, 2022 - Wiley Online Library
Salvia miltiorrhiza Bunge, a traditional Chinese medicine, is widely used in the treatment of
a variety of diseases and syndromes. Tanshinone IIA (TIIA), a phenanthrenequinone‐class …

[HTML][HTML] Effects of tanshinone IIA on fibrosis in a rat model of cirrhosis through heme oxygenase-1, inflammation, oxidative stress and apoptosis

M Shu, XR Hu, ZA Hung… - Molecular medicine …, 2016 - spandidos-publications.com
Tanshinone IIA is extracted from the root of Salvia miltiorrhiza and used in traditional
Chinese medicine for its anti-inflammatory activity and antioxidant effects. The aim of the …

Tanshinone IIA protects against immune-mediated liver injury through activation of T-cell subsets and regulation of cytokines

XY Qin, T Li, L Yan, QS Liu, Y Tian - Immunopharmacology and …, 2010 - Taylor & Francis
Background and Aim: Tanshione IIA (TSN) is the major active component of Salvia
miltiorrhiza, a traditional Chinese Medicine. TSN protects against antioxidant-induced liver …

A network pharmacology approach to investigating the mechanism of Tanshinone IIA for the treatment of liver fibrosis

MJ Shi, XL Yan, BS Dong, WN Yang, SB Su… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological revelvance Tanshinone IIA (TIIA) is a major component
extracted from the traditional herbal medicine salvia miltiorrhiza (Danshen), which activates …

[HTML][HTML] Effect of tanshinone IIA on oxidative stress and apoptosis in a rat model of fatty liver

GL Yang, LQ Jia, J Wu, YX Ma… - Experimental and …, 2017 - spandidos-publications.com
Oxidative stress is a crucial factor associated with fatty liver disease, which raises the
possibility of using antioxidants to improve liver steatosis. Tanshinone IIA (TSIIA) is a …

Tanshinone IIA inhibits Hep-J5 cells by increasing calreticulin, caspase 12 and GADD153 protein expression

CY Cheng, CC Su - International journal of molecular …, 2010 - spandidos-publications.com
Abstract Tanshinone IIA (Tan-IIA) is extracted from Danshen, Salviae miltiorrhizae Radix,
which has been widely adopted in traditional herbal medicine to treat cardiovascular and …