Elevated circulating tissue factor procoagulant activity, factor VII, and plasminogen activator inhibitor‐1 in childhood obesity: evidence of a procoagulant state
Childhood obesity is rapidly increasing in prevalence. We compared circulating membrane‐
bound tissue factor (FIII, F 3) procoagulant activity (TF‐PCA) and plasma markers of …
bound tissue factor (FIII, F 3) procoagulant activity (TF‐PCA) and plasma markers of …
Increased plasminogen activator inhibitor results in a hypofibrinolytic state in adolescents with obesity: in vivo and ex vivo evidence
K Dietrich, GDC Ball, LG Mitchell - British journal of …, 2016 - Wiley Online Library
Obesity in adolescents increases their risk for deep vein thrombosis. The objectives of this
study were to determine potential mechanisms for thrombotic risk by investigating the …
study were to determine potential mechanisms for thrombotic risk by investigating the …
Infantile obesity: a situation of atherothrombotic risk?
M Valle, F Gascón, R Martos, FJ Ruz, F Bermudo… - Metabolism, 2000 - Elsevier
Obesity is a major risk factor for cardiovascular disease frequently associated with
hypertension, dyslipidemia, and diabetes. In recent years, alterations in the hemostatic …
hypertension, dyslipidemia, and diabetes. In recent years, alterations in the hemostatic …
Evidence that fibrinolytic changes in paediatric obesity translate into a hypofibrinolytic state
F Semeraro, P Giordano, MF Faienza… - Thrombosis and …, 2012 - thieme-connect.com
Paediatric obesity, like adulthood obesity, is associated with an increase of fibrinolysis
inhibitors. No study, however, has evaluated the impact of these changes on plasma …
inhibitors. No study, however, has evaluated the impact of these changes on plasma …
Increased coagulation in childhood obesity
Objective: This study aims to explore the relation between childhood obesity and
procoagulant and anticoagulant systems. Method: Fifty-one obese children and 32 normal …
procoagulant and anticoagulant systems. Method: Fifty-one obese children and 32 normal …
Haemostatic alterations in overweight children: associations between metabolic syndrome, thrombin generation, and fibrinogen levels
P Fritsch, M Kleber, A Rosenkranz, M Fritsch… - Atherosclerosis, 2010 - Elsevier
BACKGROUND: The metabolic syndrome (MetS) is associated with central obesity and
leads to increased morbidity and mortality due to cardiovascular disease (CVD). Since …
leads to increased morbidity and mortality due to cardiovascular disease (CVD). Since …
Normalization of haemostatic alterations in overweight children with weight loss due to lifestyle intervention
P Fritsch, M Kleber, A Schlagenhauf, B Laschnik… - Atherosclerosis, 2011 - Elsevier
BACKGROUND: Obesity has been shown to be associated with a hypercoagulable state.
However, the effect of weight loss on these haemostatic alterations has not been studied yet …
However, the effect of weight loss on these haemostatic alterations has not been studied yet …
[HTML][HTML] Response of fractional synthesis rate (FSR) of fibrinogen, concentration of D‐dimer and fibrinolytic balance to physical activity‐based intervention in obese …
P Balagopal, D George, S Sweeten, KJ Mann… - Journal of Thrombosis …, 2008 - Elsevier
Background: Physical activity‐induced reduction in obesity‐related hyperfibrinogenemia in
children has been reported. The underlying mechanisms remain elusive. Further, the effect …
children has been reported. The underlying mechanisms remain elusive. Further, the effect …
Significant associations among hemostatic parameters, adipokines, and components of the metabolic syndrome in Japanese preschool children
H Horigome, Y Katayama… - Clinical and Applied …, 2012 - journals.sagepub.com
Development of cardiovascular diseases could originate in early childhood. However,
reference values of hemostatic parameters and adipokines in preschool children remain to …
reference values of hemostatic parameters and adipokines in preschool children remain to …
Insulin resistance is associated with at least threefold increased risk for prothrombotic state in severely obese youngsters
A Galli-Tsinopoulou, I Kyrgios, I Maggana… - European journal of …, 2011 - Springer
Obesity in childhood increases the risk for early adult cardiovascular disease. However, the
underlying mechanism is not fully known. The aims of this study were to measure levels of …
underlying mechanism is not fully known. The aims of this study were to measure levels of …