Investigating TSPO levels in occupation-related posttraumatic stress disorder
SE Watling, T Gill, EV Gaudette, JD Richardson… - Scientific reports, 2023 - nature.com
Microglia are immune brain cells implicated in stress-related mental illnesses including
posttraumatic stress disorder (PTSD). Their role in the pathophysiology of PTSD, and on …
posttraumatic stress disorder (PTSD). Their role in the pathophysiology of PTSD, and on …
PTSD is associated with neuroimmune suppression: evidence from PET imaging and postmortem transcriptomic studies
Despite well-known peripheral immune activation in posttraumatic stress disorder (PTSD),
there are no studies of brain immunologic regulation in individuals with PTSD.[11C] PBR28 …
there are no studies of brain immunologic regulation in individuals with PTSD.[11C] PBR28 …
The association of psychosocial risk factors for mental health with a brain marker altered by inflammation: A translocator protein (TSPO) PET imaging study
T Dahoun, MA Calcia, M Veronese, P Bloomfield… - Brain, Behavior, and …, 2019 - Elsevier
Psychiatric disorders associated with psychosocial risk factors, including depression and
psychosis, have been shown to demonstrate increased microglia activity. Whilst preclinical …
psychosis, have been shown to demonstrate increased microglia activity. Whilst preclinical …
Personality traits in psychosis and psychosis risk linked to TSPO expression: A neuroimmune marker
C Gerritsen, Y Iyengar, T DaSilva, A Koppel… - Personality …, 2020 - cambridge.org
Personality has been correlated with differences in cytokine expression, an indicator of
peripheral inflammation; however, the associations between personality and central markers …
peripheral inflammation; however, the associations between personality and central markers …
[HTML][HTML] Neuroinflammation in World Trade Center responders at midlife: a pilot study using [18F]-FEPPA PET imaging
Y Deri, SAP Clouston, C DeLorenzo… - Brain, Behavior, & …, 2021 - Elsevier
Background Neuroinflammation has long been theorized to arise from exposures to fine
particulate matter and to be modulated when individuals experience chronic stress, both of …
particulate matter and to be modulated when individuals experience chronic stress, both of …
TSPO expression and brain structure in the psychosis spectrum
Psychosis is associated with abnormal structural changes in the brain including decreased
regional brain volumes and abnormal brain morphology. However, the underlying causes of …
regional brain volumes and abnormal brain morphology. However, the underlying causes of …
Microglial deletion and inhibition alleviate behavior of post-traumatic stress disorder in mice
S Li, Y Liao, Y Dong, X Li, J Li, Y Cheng… - Journal of …, 2021 - Springer
Background Alteration of immune status in the central nervous system (CNS) has been
implicated in the development of post-traumatic stress disorder (PTSD). However, the nature …
implicated in the development of post-traumatic stress disorder (PTSD). However, the nature …
Post-traumatic stress disorder: focus on neuroinflammation
J Li, L Tong, BC Schock, LL Ji - Molecular Neurobiology, 2023 - Springer
Post-traumatic stress disorder (PTSD), gaining increasing attention, is a multifaceted
psychiatric disorder that occurs following a stressful or traumatic event or series of events …
psychiatric disorder that occurs following a stressful or traumatic event or series of events …
Imaging of astrocytes in posttraumatic stress disorder: A PET study with the monoamine oxidase B radioligand [11C] SL25. 1188
T Gill, SE Watling, JD Richardson, T McCluskey… - European …, 2022 - Elsevier
Posttraumatic stress disorder (PTSD) is a debilitating mental health condition that results
from exposure to traumatic event (s). Decreased astrocyte-related proteins (eg, glial fibrillary …
from exposure to traumatic event (s). Decreased astrocyte-related proteins (eg, glial fibrillary …
Microglia Loss and Astrocyte Activation Cause Dynamic Changes in Hippocampal [18F]DPA-714 Uptake in Mouse Models of Depression
J Guo, T Qiu, L Wang, L Shi, M Ai, Z Xia… - Frontiers in cellular …, 2022 - frontiersin.org
Major depression is a serious and chronic mental illness. However, its etiology is poorly
understood. Although glial cells have been increasingly implicated in the pathogenesis of …
understood. Although glial cells have been increasingly implicated in the pathogenesis of …