Ongoing research has highlighted the significance of the cross-play of macrophages and
mesenchymal stem cells (MSCs). Lysine-specific demethylase 6B (KDM6B) has been …

Activating autologous stem cells after the implantation of biomaterials is an important
process to initiate bone regeneration. Although several studies have demonstrated the …

Skeletal tissue originates from mesenchymal stem cells (MSCs) with differentiation potential
into the osteoblast lineage regulated by essential transcriptional and post‐transcriptional …

Objective Mesenchymal stem cells (MSCs) confer therapeutic benefits in various
pathologies and cancers by releasing extracellular vesicles (EVs) loaded with bioactive …

The dialogue between host macrophages (Mφs) and endogenous mesenchymal stem cells
(MSCs) promotes M2 Mφs polarization to resolve early-stage inflammation, thereby …

Understanding the bone and musculoskeletal system is essential to maintain the health and
quality of life of our aging society. Mesenchymal stem cells (MSCs) can undergo self …

Although BMP9 is highly capable of promoting osteogenic differentiation of mesenchymal
stem cell (MSCs), the molecular mechanism involved remains to be fully elucidated. Here …

Aims The efficacy of anti-osteoporotic treatments is still limited. Our study aimed to
investigate the effect of extracellular vesicles (EVs) derived from bone marrow-derived …

Abstract Bone morphogenetic protein 2 (BMP2) effectively induced mesenchymal stem cells
(MSCs) osteogenic differentiation hold great potential for bone tissue engineering. However …

Skeletal aging is a complex process, characterized by a decrease in bone formation, an
increase in marrow fat, and stem cell exhaustion. Loss of H3K9me3, a heterochromatin …