Stability enhancement of fluorophores for lighting up practical application in bioimaging

X Wu, W Zhu - Chemical Society Reviews, 2015 - pubs.rsc.org
The practical application of organic fluorophores in bioimaging is severely limited due to
their generally poor stability. In this Highlight, we emphasize several representative …

Highly fluorescent and bioresorbable polymeric nanoparticles with enhanced photostability for cell imaging

S Huang, S Liu, K Wang, C Yang, Y Luo, Y Zhang… - Nanoscale, 2015 - pubs.rsc.org
We report a facile and general strategy for enhancing the photostability of organic
fluorophores for bioimaging applications. As a proof of concept, bright and robust …

Chemical approaches to optimize the properties of organic fluorophores for imaging and sensing

G Jiang, H Liu, H Liu, G Ke, TB Ren… - Angewandte …, 2024 - Wiley Online Library
Organic fluorophores are indispensable tools in cells, tissue and in vivo imaging, and have
enabled much progress in the wide range of biological and biomedical fields. However …

Ultra-stable organic fluorophores for single-molecule research

Q Zheng, MF Juette, S Jockusch… - Chemical Society …, 2014 - pubs.rsc.org
Fluorescence provides a mechanism for achieving contrast in biological imaging that
enables investigations of molecular structure, dynamics, and function at high spatial and …

Chronological development of functional fluorophores for bio-imaging

S Munan, YT Chang, A Samanta - Chemical Communications, 2023 - pubs.rsc.org
Functional fluorophores represent an emerging research field, distinguished by their diverse
applications, especially in sensing and cellular imaging. After the discovery of Quinine …

Brightness and Photostability of Emerging Red and Near‐IR Fluorescent Nanomaterials for Bioimaging

P Reineck, A Francis, A Orth, DWM Lau… - Advanced Optical …, 2016 - Wiley Online Library
Many novel fluorescent nanomaterials exhibit radically different optical properties compared
to organic fluorophores that are still the most extensively used class of fluorophores in …

Development of photostable fluorophores for molecular imaging

Q Zheng, LD Lavis - Current opinion in chemical biology, 2017 - Elsevier
Highlights•Modern microscopy methods require fluorescent labels with increased
photostability.•The photobleaching of fluorophores often involves the first triplet-excited state …

Self-assembled biocompatible fluorescent nanoparticles for bioimaging

V Caponetti, JW Trzcinski, A Cantelli, R Tavano… - Frontiers in …, 2019 - frontiersin.org
Fluorescence is a powerful tool for mapping biological events in real-time with high spatial
resolution. Ultra-bright probes are needed in order to achieve high sensitivity: these probes …

Organic fluorescent dye-based nanomaterials: advances in the rational design for imaging and sensing applications

D Svechkarev, AM Mohs - Current medicinal chemistry, 2019 - ingentaconnect.com
Self-assembled fluorescent nanomaterials based on small-molecule organic dyes are
gaining increasing popularity in imaging and sensing applications over the past decade …

Bright and stable Cy3-encapsulated fluorescent silica nanoparticles with a large Stokes shift

G Chen, F Song, X Wang, S Sun, J Fan, X Peng - Dyes and Pigments, 2012 - Elsevier
Traditional organic fluorophores, like cyanine dyes, suffer from their poor stability and weak
brightness of individual molecule. In this work, a novel cyanine dye with a large Stokes shift …