Effects of chronic exposure to microcystin-LR on kidney in mice
X Yi, S Xu, F Huang, C Wen, S Zheng, H Feng… - International journal of …, 2019 - mdpi.com
Microcystin-LR (MC-LR) is a potent hepatotoxin, but a few studies suggested that it might
also induce nephrotoxicity. However, nephrotoxicity induced by prolonged oral exposure to …
also induce nephrotoxicity. However, nephrotoxicity induced by prolonged oral exposure to …
[HTML][HTML] Chronic exposure to low concentration of MC-LR caused hepatic lipid metabolism disorder
C Du, S Zheng, Y Yang, X Feng, J Chen, Y Tang… - Ecotoxicology and …, 2022 - Elsevier
Abstract Microcystin-LR (MC-LR), a potent hepatotoxin can cause liver damages. However,
research on hepatic lipid metabolism caused by long-term exposure to environmental …
research on hepatic lipid metabolism caused by long-term exposure to environmental …
Hepatic and intestine alterations in mice after prolonged exposure to low oral doses of Microcystin-LR
D Sedan, M Laguens, G Copparoni, JO Aranda… - Toxicon, 2015 - Elsevier
Oral intake of Microcystin-LR (MC-LR) is the principal route of exposure to this toxin, with
prolonged exposure leading to liver damage of unspecific symptomatology. The aim of the …
prolonged exposure leading to liver damage of unspecific symptomatology. The aim of the …
Microcystin-LR-induced cytotoxicity and apoptosis in human embryonic kidney and human kidney adenocarcinoma cell lines
M Piyathilaka, MM Pathmalal… - …, 2015 - microbiologyresearch.org
Microcystin-LR (MC-LR) is a potent hepatotoxin, and increasing evidence suggests that it
might also induce kidney injury. The aim of the present work was to evaluate the cytotoxicity …
might also induce kidney injury. The aim of the present work was to evaluate the cytotoxicity …
Uptake and accumulation of Microcystin-LR based on exposure through drinking water: An animal model assessing the human health risk
B Greer, JP Meneely, CT Elliott - Scientific reports, 2018 - nature.com
Abstract Harmful Algal Blooms (HABs) in freshwater systems and intensified aquaculture
have increased the risk to human health through exposure to cyanotoxins such as …
have increased the risk to human health through exposure to cyanotoxins such as …
Microcystin-LR combined with cadmium exposures and the risk of chronic kidney disease: a case–control study in Central China
S Feng, S Deng, Y Tang, Y Liu, Y Yang… - Environmental …, 2022 - ACS Publications
Increasing evidence indicates that exposure to microcystin-LR (MC-LR) can cause kidney
damage. However, the association between MC-LR exposure and chronic kidney disease …
damage. However, the association between MC-LR exposure and chronic kidney disease …
Nephrotoxic effects of chronic administration of microcystins-LR and-YR
A Milutinović, M Živin, R Zorc-Pleskovič, B Sedmak… - Toxicon, 2003 - Elsevier
Acute intoxication with MC-LR induces cytoskeletal alterations, apoptosis and necrosis of
hepatocytes resulting in intrahepatic hemorrhage. Preliminary results have shown that …
hepatocytes resulting in intrahepatic hemorrhage. Preliminary results have shown that …
Antioxidant enzyme activity and lipid peroxidation in liver and kidney of rats exposed to microcystin-LR administered intraperitoneally
I Moreno, S Pichardo, A Jos, L Gomez-Amores, A Mate… - Toxicon, 2005 - Elsevier
The effect of acute exposure of intraperitoneal injection of microcystin-LR (MCLR) on
antioxidant enzymes and lipid peroxidation has been studied in liver and kidney of rats. Rats …
antioxidant enzymes and lipid peroxidation has been studied in liver and kidney of rats. Rats …
First report on the distribution of orally administered microcystin-LR in mouse tissue using an immunostaining method
E Ito, F Kondo, KI Harada - Toxicon, 2000 - Elsevier
The purpose of this study was to investigate the distribution of microcystin-LR (MCLR) orally
administered to mice using an immunostaining method. MCLR was orally dosed at 500 …
administered to mice using an immunostaining method. MCLR was orally dosed at 500 …
Microcystin-LR exposure interfered maintenance of colonic microenvironmental homeostasis in rat
Microcystin-leucine arginine (MCLR) is a phycotoxin produced by cyanobacteria. As a
hepatotoxin, increasing evidence suggests that it has some negative effects on the mammal …
hepatotoxin, increasing evidence suggests that it has some negative effects on the mammal …
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