Quorum‐sensing system in Acinetobacter baumannii: a potential target for new drug development

K Saipriya, CH Swathi, KS Ratnakar… - Journal of applied …, 2020 - academic.oup.com
Acinetobacter baumannii causes several nosocomial infections and poses major threat
when it is multidrug resistant. Even pan drug‐resistant strains have been reported in some …

Quorum Sensing Inhibition or Quenching in Acinetobacter baumannii: The Novel Therapeutic Strategies for New Drug Development

S Zhong, S He - Frontiers in Microbiology, 2021 - frontiersin.org
Acinetobacter baumannii is a Gram-negative opportunistic nosocomial pathogen, which can
cause ventilator-related and blood infection in critically ill patients. The resistance of A …

Quenching the quorum sensing system: potential antibacterial drug targets

VC Kalia, HJ Purohit - Critical reviews in microbiology, 2011 - Taylor & Francis
Emergence of antibiotic and multi-drug resistant pathogenic bacteria has created the need
for new drugs and drug targets. During pathogenesis bacteria release signals which …

Quorum sensing pathways in Gram-positive and-negative bacteria: potential of their interruption in abating drug resistance

S Haque, DK Yadav, SC Bisht, N Yadav… - Journal of …, 2019 - Taylor & Francis
Quorum sensing (QS) is an inter-cell communication between bacterial populations through
release of tiny diffusible compounds as signalling agents, called auto-inducers, abetting …

Drugs with new lease of life as quorum sensing inhibitors: for combating MDR Acinetobacter baumannii infections

NM Seleem, HK Abd El Latif, MA Shaldam… - European Journal of …, 2020 - Springer
The emergence of multidrug-resistant (MDR) strains is a major health problem worldwide.
There is an urgent need for novel strategies to combat bacterial infections caused by MDR …

[HTML][HTML] Quorum quenching: a drug discovery approach against Pseudomonas aeruginosa

MA Rather, D Saha, S Bhuyan, AN Jha… - Microbiological …, 2022 - Elsevier
Pseudomonas aeruginosa, a ubiquitous opportunistic and nosocomial biofilm-forming
pathogen with complex, interconnected and hierarchical nature of QS systems (Las, Rhl …

Bacterial quorum sensing inhibitors: attractive alternatives for control of infectious pathogens showing multiple drug resistance

AK Bhardwaj, K Vinothkumar… - Recent patents on anti …, 2013 - ingentaconnect.com
Quorum sensing (QS) is a bacterial communication process that depends on the bacterial
population density. It involves small diffusible signaling molecules which activate the …

Resistance to quorum-quenching compounds

R García-Contreras, T Maeda… - Applied and …, 2013 - Am Soc Microbiol
Bacteria have the remarkable ability to communicate as a group in what has become known
as quorum sensing (QS), and this trait has been associated with important bacterial …

Quorum sensing inhibitors: a bargain of effects

TB Rasmussen, M Givskov - Microbiology, 2006 - microbiologyresearch.org
Many opportunistic pathogenic bacteria rely on quorum sensing (QS) circuits as central
regulators of virulence expression. In Pseudomonas aeruginosa, QS-regulated gene …

Developments in strategies for Quorum Sensing virulence factor inhibition to combat bacterial drug resistance

S Haque, F Ahmad, SA Dar, A Jawed, RK Mandal… - Microbial …, 2018 - Elsevier
Quorum sensing (QS) is a complex bacterial intercellular communication system. It is
mediated by molecules called auto-inducers (AIs) and allows coordinated responses to a …