Novel thermosensitive hydrogel promotes spinal cord repair by regulating mitochondrial function
Y Li, L Yang, F Hu, J Xu, J Ye, S Liu… - … Applied Materials & …, 2022 - ACS Publications
The repair of spinal cord injury (SCI) is still a tough clinical challenge and needs innovative
therapies. Mitochondrial function is significantly compromised after SCI and has emerged as …
therapies. Mitochondrial function is significantly compromised after SCI and has emerged as …
A chitosan-based thermosensitive scaffold loaded with bone marrow-derived mesenchymal stem cells promotes motor function recovery in spinal cord injured mice
J Zhang, T Cheng, Y Chen, F Gao, F Guan… - Biomedical …, 2020 - iopscience.iop.org
Spinal cord injury is a devastating trauma with high mortality and disability, for which there is
no effective treatment. Stem cell-based tissue engineering has been reported to promote …
no effective treatment. Stem cell-based tissue engineering has been reported to promote …
An electroconductive hydrogel scaffold with injectability and biodegradability to manipulate neural stem cells for enhancing spinal cord injury repair
H Liu, Y Feng, S Che, L Guan, X Yang, Y Zhao… - …, 2022 - ACS Publications
Spinal cord injury (SCI) generally leads to long-term functional deficits and is difficult to
repair spontaneously. Many biological scaffold materials and stem cell treatment strategies …
repair spontaneously. Many biological scaffold materials and stem cell treatment strategies …
Dual-enzymatically cross-linked gelatin hydrogel enhances neural differentiation of human umbilical cord mesenchymal stem cells and functional recovery in …
M Yao, J Li, J Zhang, S Ma, L Wang, F Gao… - Journal of Materials …, 2021 - pubs.rsc.org
Recently, an advanced stem cell and tissue engineering approach has been recognized as
an emerging and fascinating strategy to promote neural repair in spinal cord injury (SCI) …
an emerging and fascinating strategy to promote neural repair in spinal cord injury (SCI) …
[HTML][HTML] An injectable heparin-Laponite hydrogel bridge FGF4 for spinal cord injury by stabilizing microtubule and improving mitochondrial function
C Wang, Z Gong, X Huang, J Wang, K Xia, L Ying… - Theranostics, 2019 - ncbi.nlm.nih.gov
Rationale: Spinal cord injury (SCI) remains a critical clinical challenge. The controlled
release of FGF4, a novel neuroprotective factor, from a versatile Laponite hydrogel to the …
release of FGF4, a novel neuroprotective factor, from a versatile Laponite hydrogel to the …
A thermosensitive heparin-poloxamer hydrogel bridges aFGF to treat spinal cord injury
Q Wang, Y He, Y Zhao, H Xie, Q Lin, Z He… - … Applied Materials & …, 2017 - ACS Publications
Acidic fibroblast growth factor (aFGF) exerts a protective effect on spinal cord injury (SCI) but
is limited by the lack of physicochemical stability and the ability to cross the blood spinal …
is limited by the lack of physicochemical stability and the ability to cross the blood spinal …
A decellularized spinal cord extracellular matrix-gel/GelMA hydrogel three-dimensional composite scaffold promotes recovery from spinal cord injury via synergism …
W He, X Zhang, X Li, D Ju, T Mao, Y Lu, Y Gu… - Journal of Materials …, 2022 - pubs.rsc.org
Spinal cord injury (SCI), as a serious disabling disease, is still haunted by lacking of effective
treatments. We previously found that transplantation of menstrual blood-derived …
treatments. We previously found that transplantation of menstrual blood-derived …
Restoration of spinal cord biophysical microenvironment for enhancing tissue repair by injury-responsive smart hydrogel
C Fan, W Yang, L Zhang, H Cai, Y Zhuang, Y Chen… - Biomaterials, 2022 - Elsevier
Spinal cord injury (SCI) represents a central nervous system disaster, resulting in the
destruction of spinal cord structure and function and the formation of an adverse …
destruction of spinal cord structure and function and the formation of an adverse …
Multimodal therapy strategy based on a bioactive hydrogel for repair of spinal cord injury
Traumatic spinal cord injury results in permanent and serious neurological impairment, but
there is no effective treatment yet. Tissue engineering approaches offer great potential for …
there is no effective treatment yet. Tissue engineering approaches offer great potential for …
[HTML][HTML] A conductive supramolecular hydrogel creates ideal endogenous niches to promote spinal cord injury repair
B Yang, C Liang, D Chen, F Cheng, Y Zhang, S Wang… - Bioactive materials, 2022 - Elsevier
The current effective method for treatment of spinal cord injury (SCI) is to reconstruct the
biological microenvironment by filling the injured cavity area and increasing neuronal …
biological microenvironment by filling the injured cavity area and increasing neuronal …