Design principles and fundamental understanding of biosensors for amyloid-β detection

Y Zhang, B Ren, D Zhang, Y Liu, M Zhang… - Journal of Materials …, 2020 - pubs.rsc.org
Alzheimer's disease (AD), as an age-related, progressive neurodegenerative disease,
poses substantial challenges and burdens on public health and disease research. While …

Detection of Aβ monomers and oligomers: early diagnosis of Alzheimer's disease

Y Zhou, L Liu, Y Hao, M Xu - Chemistry–An Asian Journal, 2016 - Wiley Online Library
Abstract Alzheimer's disease (AD), as the most common progressive neurodegenerative
disorder, is pathologically characterized by deposition of extracellular plaque composed of …

Amyloid-based nanosensors and nanodevices

CAE Hauser, S Maurer-Stroh, IC Martins - Chemical Society Reviews, 2014 - pubs.rsc.org
Self-assembling amyloid-like peptides and proteins give rise to promising biomaterials with
potential applications in many fields. Amyloid structures are formed by the process of …

Functional Nanomaterials for the Diagnosis of Alzheimer's Disease: Recent Progress and Future Perspectives

SA Abdullah, L Najm, L Ladouceur… - Advanced Functional …, 2023 - Wiley Online Library
Alzheimer's disease (AD) is one of the main causes of dementia worldwide, whereby
neuronal death or malfunction leads to cognitive impairment in the elderly population. AD is …

Nano-biosensors to detect beta-amyloid for Alzheimer's disease management

A Kaushik, RD Jayant, S Tiwari, A Vashist… - Biosensors and …, 2016 - Elsevier
Abstract Beta-amyloid (β-A) peptides are potential biomarkers to monitor Alzheimer's
diseases (AD) for diagnostic purposes. Increased β-A level is neurotoxic and induces …

Current strategies of detecting Aβ species and inhibiting Aβ aggregation: Status and prospects

J Li, W Liao, D Huang, M Ou, T Chen, X Wang… - Coordination Chemistry …, 2023 - Elsevier
Alzheimer's disease (AD) is a central neurodegenerative disorder characterized by
behavioral disturbance and progressive cognitive impairment, and it is common in pre …

[HTML][HTML] Clinically oriented Alzheimer's biosensors: expanding the horizons towards point-of-care diagnostics and beyond

BT Murti, AD Putri, YJ Huang, SM Wei, CW Peng… - RSC …, 2021 - pubs.rsc.org
The development of minimally invasive and easy-to-use sensor devices is of current interest
for ultrasensitive detection and signal recognition of Alzheimer's disease (AD) biomarkers …

Biosensors on the road to early diagnostic and surveillance of Alzheimer's disease

P Carneiro, S Morais, M do Carmo Pereira - Talanta, 2020 - Elsevier
Alzheimer's disease is a debilitating and largely untreatable condition with subtle onset and
slow progression over an extensive period of time, which culminate in increasing levels of …

Nanomaterial-based Optical and Electrochemical Biosensors for Amyloid beta and Tau: Potential for early diagnosis of Alzheimer's Disease

LMT Phan, TX Hoang, TAT Vo, HL Pham… - Expert Review of …, 2021 - Taylor & Francis
Introduction Alzheimer's disease (AD), a heterogeneous pathological process representing
the most common causes of dementia worldwide, has required early and accurate …

Chemical sensing platforms for detecting trace-level Alzheimer's core biomarkers

K Kim, CH Lee, CB Park - Chemical Society Reviews, 2020 - pubs.rsc.org
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder and affects more
than 10% of the population aged over 65 worldwide. Despite considerable global efforts, AD …