In a quest for bivalent mRNA vaccine for respiratory viruses: An effective strategy to overcome antigenic competition
G Mahalingam, S Marepally - Molecular Therapy, 2024 - cell.com
In a world grappling with the evolving variants of severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), another emerging respiratory virus, respiratory syncytial virus …
coronavirus 2 (SARS-CoV-2), another emerging respiratory virus, respiratory syncytial virus …
A potential bivalent mRNA vaccine candidate protects against both RSV and SARS-CoV-2 infections
N Wu, J Zhang, Y Shen, X Zhang, J Zhou, Y Wu, E Li… - Molecular Therapy, 2024 - cell.com
As the world continues to confront severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2), respiratory syncytial virus (RSV) is also causing severe respiratory illness in millions …
CoV-2), respiratory syncytial virus (RSV) is also causing severe respiratory illness in millions …
Design of SARS-CoV-2 hFc-Conjugated Receptor-Binding Domain mRNA Vaccine Delivered via Lipid Nanoparticles
U Elia, S Ramishetti, R Rosenfeld, N Dammes… - ACS …, 2021 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been identified as the
causal agent of COVID-19 and stands at the center of the current global human pandemic …
causal agent of COVID-19 and stands at the center of the current global human pandemic …
The Nobel Prize awarded to pioneers of mRNA vaccines
RW Herzog, PH Giangrande - Molecular Therapy, 2023 - cell.com
In 2020, the emerging threat to humanity posed by the rapidly evolving COVID-19 pandemic
called for accelerated development of vaccines at unprecedented speeds. While far less …
called for accelerated development of vaccines at unprecedented speeds. While far less …
Optimization of an LNP-mRNA vaccine candidate targeting SARS-CoV-2 receptor-binding domain
K Kobiyama, M Imai, N Jounai, M Nakayama, K Hioki… - bioRxiv, 2021 - biorxiv.org
In 2020, two mRNA-based vaccines, encoding the full length of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) spike protein, have been introduced for control of …
syndrome coronavirus 2 (SARS-CoV-2) spike protein, have been introduced for control of …
Monovalent SARS-COV-2 mRNA vaccine using optimal UTRs and LNPs is highly immunogenic and broadly protective against Omicron variants
The emergence of highly transmissible severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) variants of concern (VOCs) that are resistant to the current COVID-19 …
(SARS-CoV-2) variants of concern (VOCs) that are resistant to the current COVID-19 …
Universal protection against SARS-CoV-2 viruses by multivalent mRNA vaccine in mice
The continual emergence of new severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) variants challenges available SARS-CoV-2 vaccines for adequate control of …
CoV-2) variants challenges available SARS-CoV-2 vaccines for adequate control of …
Broad protection and respiratory immunity of dual mRNA vaccination against SARS-CoV-2 variants
A broadly protective vaccine for COVID-19 is needed to end the pandemic and to prevent its
future recurrence. While the first-generation, spike-based vaccines are effective against …
future recurrence. While the first-generation, spike-based vaccines are effective against …
[HTML][HTML] A Unique mRNA Vaccine Elicits Protective Efficacy against the SARS-CoV-2 Omicron Variant and SARS-CoV
The highly pathogenic coronaviruses SARS-CoV-2 and SARS-CoV have led to the COVID-
19 pandemic and SARS outbreak, respectively. The receptor-binding domain (RBD) of the …
19 pandemic and SARS outbreak, respectively. The receptor-binding domain (RBD) of the …
[HTML][HTML] mRNA-based SARS-CoV-2 vaccine candidate CVnCoV induces high levels of virus-neutralising antibodies and mediates protection in rodents
S Rauch, N Roth, K Schwendt, M Fotin-Mleczek… - npj Vaccines, 2021 - nature.com
Abstract mRNA technologies have recently proven clinical efficacy against coronavirus
disease 2019 and are among the most promising technologies to address the current …
disease 2019 and are among the most promising technologies to address the current …
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