[PDF][PDF] Role of DNA methylation in the regulation of SLC22A17 in cutaneous melanoma

S CANDIDO, S STEFANI - iris.unict.it
Cutaneous melanoma represents one of the deadliest forms of skin cancer due to its high
invasiveness and metastatic tendency. Despite recent advances in screening programs and …

[HTML][HTML] Bioinformatic analysis of the LCN2–SLC22A17–MMP9 network in cancer: The role of DNA methylation in the modulation of tumor microenvironment

S Candido, B Tomasello, A Lavoro… - Frontiers in Cell and …, 2022 - frontiersin.org
Several features of cancer cells such as proliferation, invasion, metastatic spreading, and
drug resistance are affected by their interaction with several tumor microenvironment (TME) …

[PDF][PDF] Identification and Validation of DNA Methylation Hotspots as Biomarkers for Cutaneous Melanoma

CMOPM LIBRA, CMAPS STEFANI - iris.unict.it
Cutaneous melanoma represents the most aggressive skin cancer due to its high invasive
and metastatic behavior. Despite the adoption of novel screening programs and the …

[HTML][HTML] New frontiers in melanoma epigenetics—the more we know, the more we don't know

M Nguyen, P Dobosz - Epigenomes, 2017 - mdpi.com
Skin cancer is one of the most common neoplasms worldwide, with a surprising tendency to
increase its incidence. As with many cancer types nowadays, early diagnosis and proper …

DNA hypermethylation is associated with invasive phenotype of malignant melanoma

V Koroknai, I Szász… - Experimental …, 2020 - Wiley Online Library
Tumor cell invasion is one of the key processes during cancer progression, leading to life‐
threatening metastatic lesions in melanoma. As methylation of cancer‐related genes plays a …

[HTML][HTML] Intra-tumoral expression of SLC7A11 is associated with immune microenvironment, drug resistance, and prognosis in cancers: a pan-cancer analysis

J He, H Ding, H Li, Z Pan, Q Chen - Frontiers in Genetics, 2021 - frontiersin.org
While many anti-cancer modalities have shown potent efficacy in clinical practices, cancer
prevention, timely detection, and effective treatment are still challenging. As a newly …

[HTML][HTML] Overexpression of SLC25A15 is involved in the proliferation of cutaneous melanoma and leads to poor prognosis

S Ji - médecine/sciences, 2018 - medecinesciences.org
Melanoma is a skin tumor with a high degree of malignancy, poor prognosis and few
effective therapies. Deprivation of the arginine from cancer cells through transport inhibition …

Epigenetic markers in melanoma

W Guo, T Xu, JJ Lee, GF Murphy… - Melanoma Management, 2015 - Future Medicine
Melanoma, one of the most virulent forms of human malignancy, is the primary cause of
mortality from cancers arising from the skin. The prognosis of metastatic melanoma remains …

Aberrant DNA methylation in malignant melanoma

C Schinke, Y Mo, Y Yu, K Amiri, J Sosman… - Melanoma …, 2010 - journals.lww.com
Malignant melanoma remains one of the most deadly human cancers with no effective cures
for metastatic disease. The poor efficacy of current therapy in advanced melanoma …

[HTML][HTML] Effects of RNA methylation N6-methyladenosine regulators on malignant progression and prognosis of melanoma

J Liu, Z Zhou, L Ma, C Li, Y Lin, T Yu, JF Wei… - Cancer Cell …, 2021 - Springer
Background Melanoma is an extremely aggressive type of skin cancer and experiencing a
expeditiously rising mortality in a current year. Exploring new potential prognostic …