Several cellular and molecular mechanisms have been implicated in migraine
pathophysiology including abnormal neuronal excitability and vascular events. Drugs from …

A variety of drugs from diverse pharmacological classes are in use for migraine prevention.
Traditionally, they have been discovered by serendipity. Examples include β‐adrenergic …

Frequent, severe and long-lasting migraine attacks require prophylaxis. Established drugs
used for the prevention of migraine such as β-adrenoceptor antagonists (β-blockers) …

A relatively high number of different medications is currently used for migraine prevention in
clinical practice. Although these compounds were initially developed for other indications …

Migraine is a paroxysmal disorder with attacks of headache, nausea, vomiting, photo-and
phonophobia and malaise. This review summarises new treatment options both for the …

Migraine therapeutics are pharmacological, including acute and preventive,
nonpharmacological and/or both. Preventive pharmacological strategies serendipitously …

Migraine is a common neurological disorder that afflicts≥ 12% of the adult US population.
Severe, frequent and disabling attacks require effective prophylaxis. Traditional preventive …

In this paper, new treatment options for migraine prevention are reviewed. An overview
about migraine pathophysiology is provided and current indications for migraine prevention …

Background: Migraine is among the 10 most disabling disorders worldwide. Besides acute
attack treatment, drug prophylaxis of migraine is important in order to improve the quality of …

• Oral medications traditionally used for the prevention of migraine and known to be effective
include anti-epileptic, β-blocker, antihypertensive and antidepressant drugs.• …