DNA methylation at the suppressor of cytokine signaling 3 (SOCS3) gene influences height in childhood
P Issarapu, M Arumalla, HR Elliott… - Nature …, 2023 - nature.com
Human height is strongly influenced by genetics but the contribution of modifiable epigenetic
factors is under-explored, particularly in low and middle-income countries (LMIC). We …
factors is under-explored, particularly in low and middle-income countries (LMIC). We …
Methylation of SOCS3 is inversely associated with metabolic syndrome in an epigenome-wide association study of obesity
O Ali, D Cerjak, JW Kent Jr, R James, J Blangero… - Epigenetics, 2016 - Taylor & Francis
Epigenetic mechanisms, including DNA methylation, mediate the interaction between gene
and environment and may play an important role in the obesity epidemic. We assessed the …
and environment and may play an important role in the obesity epidemic. We assessed the …
DNA methylation near MAD1L1, KDM2B, and SOCS3 mediates the effect of socioeconomic status on elevated body mass index in African American adults
LS Glover, AG Lilly, AE Justice… - Human Molecular …, 2024 - academic.oup.com
Obesity and poverty disproportionally affect African American persons. Epigenetic
mechanisms could partially explain the association between socioeconomic disadvantage …
mechanisms could partially explain the association between socioeconomic disadvantage …
Associations between epigenome-wide DNA methylation and height-related traits among Sub-Saharan Africans: the RODAM study
G Swart, K Meeks, F Chilunga, A Venema… - … origins of health and …, 2023 - cambridge.org
Human height and related traits are highly complex, and extensively research has shown
that these traits are determined by both genetic and environmental factors. Such factors may …
that these traits are determined by both genetic and environmental factors. Such factors may …
Adult height variants affect birth length and growth rate in children
Previous studies identified 180 single nucleotide polymorphisms (SNPs) associated with
adult height, explaining∼ 10% of the variance. The age at which these begin to affect …
adult height, explaining∼ 10% of the variance. The age at which these begin to affect …
Epigenetic heredity of human height
Genome‐wide SNP analyses have identified genomic variants associated with adult human
height. However, these only explain a fraction of human height variation, suggesting that …
height. However, these only explain a fraction of human height variation, suggesting that …
Socioeconomic status and DNA methylation from birth through mid-childhood: a prospective study in Project Viva
Aim: We investigated associations of prenatal socioeconomic status (SES) with DNA
methylation at birth, and to explore persistence of associations into early (∼3 years) and …
methylation at birth, and to explore persistence of associations into early (∼3 years) and …
Cord blood epigenome-wide meta-analysis in six European-based child cohorts identifies signatures linked to rapid weight growth
Background Rapid postnatal growth may result from exposure in utero or early life to
adverse conditions and has been associated with diseases later in life and, in particular …
adverse conditions and has been associated with diseases later in life and, in particular …
Association between DNA methylation at SOCS3 gene and body mass index might be due to familial confounding
Wilson et al. 1 found, from cross-sectional analyses of data for middle-aged women from the
Sister Study cohort, that DNA methylation in blood at nine CpG sites was associated with …
Sister Study cohort, that DNA methylation in blood at nine CpG sites was associated with …
Socioeconomic position during pregnancy and DNA methylation signatures at three stages across early life: epigenome-wide association studies in the ALSPAC birth …
R Alfano, F Guida, B Galobardes… - International journal …, 2019 - academic.oup.com
Background Socioeconomic experiences are recognized determinants of health, and recent
work has shown that social disadvantages in early life may induce sustained biological …
work has shown that social disadvantages in early life may induce sustained biological …
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