Stratifying patients with peripheral neuropathic pain based on sensory profiles: algorithm and sample size recommendations

J Vollert, C Maier, N Attal, DLH Bennett, D Bouhassira… - Pain, 2017 - journals.lww.com
In a recent cluster analysis, it has been shown that patients with peripheral neuropathic pain
can be grouped into 3 sensory phenotypes based on quantitative sensory testing profiles …

Peripheral neuropathic pain: a mechanism-related organizing principle based on sensory profiles

R Baron, C Maier, N Attal, A Binder, D Bouhassira… - Pain, 2017 - journals.lww.com
Patients with neuropathic pain are heterogeneous in etiology, pathophysiology, and clinical
appearance. They exhibit a variety of painrelated sensory symptoms and signs (sensory …

Stratification of patients based on the Neuropathic Pain Symptom Inventory: development and validation of a new algorithm

D Bouhassira, S Branders, N Attal, AM Fernandes… - Pain, 2021 - journals.lww.com
The personalization of neuropathic pain treatment could be improved by identifying specific
sensory phenotypes (ie, specific combinations of symptoms and signs) predictive of the …

Individualized neuropathic pain therapy based on phenotyping: are we there yet?

J Forstenpointner, J Otto, R Baron - Pain, 2018 - journals.lww.com
Patients with the same neuropathic pain disorder may have completely different sensory
signs and symptoms yet receive the same medicinal treatment. New concepts suggest that …

Pathophysiological mechanisms of neuropathic pain: comparison of sensory phenotypes in patients and human surrogate pain models

J Vollert, W Magerl, R Baron, A Binder… - Pain, 2018 - journals.lww.com
As an indirect approach to relate previously identified sensory phenotypes of patients
suffering from peripheral neuropathic pain to underlying mechanisms, we used a published …

A cross-sectional cohort survey in 2100 patients with painful diabetic neuropathy and postherpetic neuralgia: differences in demographic data and sensory symptoms

R Baron, TR Tölle, U Gockel, M Brosz, R Freynhagen - Pain, 2009 - Elsevier
Patients with neuropathic pain syndromes are heterogeneous. They present with a variety of
sensory symptoms and pain qualities. The knowledge of these data and etiology-specific …

Personalized treatment of neuropathic pain: Where are we now?

D Bouhassira, N Attal - European Journal of Pain, 2023 - Wiley Online Library
Background The treatment of neuropathic pain remains a major unmet need that the
development of personalized and refined treatment strategies may contribute to address …

Identification of cut-points for mild, moderate and severe pain due to diabetic peripheral neuropathy

DC Zelman, E Dukes, N Brandenburg, A Bostrom… - Pain, 2005 - Elsevier
This study identified discrete categories of pain severity in a sample of patients with painful
diabetic peripheral neuropathy (DPN), through derivation of cut-points on a 0–10 scale of …

[HTML][HTML] Neuropathic pain phenotyping as a predictor of treatment response in painful diabetic neuropathy: data from the randomized, double-blind, COMBO-DN study

D Bouhassira, S Wilhelm, A Schacht, S Perrot, E Kosek… - Pain®, 2014 - Elsevier
Sensory profiles are heterogeneous in neuropathic pain disorders, and subgroups of
patients respond differently to treatment. To further explore this, patients in the COMBO-DN …

A novel tool for the assessment of pain: validation in low back pain

J Scholz, RJ Mannion, DE Hord, RS Griffin… - PLoS …, 2009 - journals.plos.org
Background Adequate pain assessment is critical for evaluating the efficacy of analgesic
treatment in clinical practice and during the development of new therapies. Yet the currently …