Staphylococcal enterotoxin A (SEA) cross-links two class II major histocompatibility complex
(MHC) molecules and forms a multimeric assembly with T-cell receptors (TcRs). The X-ray …

Although the biological properties of staphylococcal enterotoxin A (SEA) have been well
characterized, structural insights into the interaction between SEA and major …

The molecular recognition of two superantigens with class II major histocompatibility
complex molecules was simulated by using protein–protein docking. Superantigens studied …

Superantigens form complexes with major histocompatibility complex (MHC) class II
molecules and T-cell receptors resulting in extremely strong immunostimulatory properties …

Superantigens are toxins produced by Staphylococcus aureus, called staphylococcal
enterotoxins (abbreviated SEA to SEU). They can cross-link the T cell receptor (TCR) and …

The structure of a mutant form of staphylococcal enterotoxin A (SEA) has been determined to
2.1 Å resolution. The studied SEA substitution H187→ A187 (SEA H187A) leads to an …

The X-ray structure of the superantigen staphylococcal enterotoxin H (SEH) has been
determined at 1.69 Å resolution. In this paper we present two structures of zinc-free SEH …

Staphylococcal enterotoxin B is a member of a family of toxins known as superantigens that
activate a large number of T-cells (up to 20%) by cross-linking MHC class II molecules with T …

Staphylococcal enterotoxins (SEs) are superantigenic protein toxins responsible for a
number of life‐threatening diseases. The X‐ray structure of a staphylococcal enterotoxin A …

The three-dimensional structure of the complex between a T cell receptor (TCR) β chain
(mouse Vβ8. 2Jβ2. 1Cβ1) and the superantigen (SAG) staphylococcal enterotoxin C3 …