Following myocardial ischemic injury, the most effective clinical intervention is timely
restoration of blood perfusion to ischemic but viable myocardium to reduce irreversible …

Abnormalities of the microvasculature are centrally involved in the pathogenesis of some
forms of heart disease, but in others are consequences of it. Microvascular abnormalities …

Background Microvascular injury (MVI) after coronary ischemia-reperfusion is associated
with high morbidity and mortality. Both ischemia and reperfusion are involved in MVI, but to …

Since early reperfusion therapy for patients with acute myocardial infarction (AMI) was
demonstrated to decrease mortality, numerous improvements in AMI management have …

Advances in early reperfusion therapies focused on the revascularization of the ischemic
tissues, in the last decades, lead to reduced mortality in acute myocardial infarction (MI) …

The coronary circulation is both culprit and victim of acute myocardial infarction. The rupture
of an epicardial atherosclerotic plaque with superimposed thrombosis causes coronary …

As reperfusion therapies have become more widely used in acute myocardial infarction
patients, ischemia-induced myocardial damage has been markedly reduced, but reperfusion …

Cardiovascular diseases are one of the leading causes of mortality in developed countries.
Among cardiovascular disorders, myocardial infarction remains a life-threatening problem …

Despite the progress of cardiovascular medicine, ischemia-reperfusion injury can contribute
to increased mortality and prolonged hospitalization after myocardial infarction. Ischemia …

Reperfusion therapy has resulted in significant improvement in post-myocardial infarction
morbidity and mortality in over the last 4 decades. Nonetheless, it is well recognized that …