[HTML][HTML] Nanotechnology-based ocular drug delivery systems: recent advances and future prospects

S Li, L Chen, Y Fu - Journal of Nanobiotechnology, 2023 - Springer
Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …

[HTML][HTML] Overview of recent advances in nano-based ocular drug delivery

LC Liu, YH Chen, DW Lu - International Journal of Molecular Sciences, 2023 - mdpi.com
Ocular diseases profoundly impact patients' vision and overall quality of life globally.
However, effective ocular drug delivery presents formidable challenges within clinical …

Nanomaterial-based ophthalmic drug delivery

G Xie, S Lin, F Wu, J Liu - Advanced drug delivery reviews, 2023 - Elsevier
The low bioavailability and side effects of conventional drugs for eye disease necessitate the
development of efficient drug delivery systems. Accompanying the developments of …

Nanotherapies for the treatment of ocular diseases

S Reimondez-Troitiño, N Csaba, MJ Alonso… - European Journal of …, 2015 - Elsevier
The topical route is the most frequent and preferred way to deliver drugs to the eye.
Unfortunately, the very low ocular drug bioavailability (less than 5%) associated with this …

[HTML][HTML] Ocular drug delivery: a comprehensive review

S Ahmed, MM Amin, S Sayed - AAPS PharmSciTech, 2023 - Springer
The human eye is a sophisticated organ with distinctive anatomy and physiology that
hinders the passage of drugs into targeted ophthalmic sites. Effective topical administration …

[HTML][HTML] Ocular drug delivery: a clue from nanotechnology

C Bucolo, F Drago, S Salomone - Frontiers in pharmacology, 2012 - frontiersin.org
Topical administration is the most common route of ocular drug delivery. Despite its
apparent easy accessibility, the eye is well protected from foreign materials and drugs by a …

Therapeutic implications of nanomedicine for ocular drug delivery

T Meng, V Kulkarni, R Simmers, V Brar, Q Xu - Drug discovery today, 2019 - Elsevier
Delivering therapeutics to the eye is challenging on multiple levels: rapid clearance of
eyedrops from the ocular surface requires frequent instillation, which is difficult for patients; …

Target strategies for drug delivery bypassing ocular barriers

R Suri, S Beg, K Kohli - Journal of drug delivery science and technology, 2020 - Elsevier
The eye is a directly accessible sensitive organ, impairment of which causes direct effect on
the quality of life. Efficient ocular drug delivery remains a major challenge for the …

[HTML][HTML] Recent achievements in nano-based technologies for ocular disease diagnosis and treatment, review and update

M Afarid, S Mahmoodi, R Baghban - Journal of Nanobiotechnology, 2022 - Springer
Ocular drug delivery is one of the most challenging endeavors among the various available
drug delivery systems. Despite having suitable drugs for the treatment of ophthalmic …

Fundamentals, challenges, and nanomedicine‐based solutions for ocular diseases

DA Srinivasarao, G Lohiya… - Wiley Interdisciplinary …, 2019 - Wiley Online Library
The eye consists of sensitive, compactly adjoined tissue structures which act as strong
physical (static) and physiological (dynamic) barriers that prevent entry of foreign bodies into …